Difference between revisions of "YPL209C"
SGDwikiBot (talk | contribs) (Automated import of articles) |
SGDwikiBot (talk | contribs) (Automated import of articles) |
||
| Line 4: | Line 4: | ||
{|{{Prettytable}} align = 'right' width = '200px' | {|{{Prettytable}} align = 'right' width = '200px' | ||
|- | |- | ||
| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006130 YPL209C] |
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''IPL1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''IPL1 '' | ||
| Line 14: | Line 14: | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr XVI:157592..156489 | |nowrap| Chr XVI:157592..156489 | ||
| + | |- | ||
| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000006130 | ||
|} | |} | ||
<br> | <br> | ||
| − | '''Description of | + | '''Description of YPL209C:''' Aurora kinase involved in regulating kinetochore-microtubule attachments; helps maintain condensed chromosomes during anaphase and early telophase; associates with Sli15p, which promotes Ipl1p association with mitotic spindle<ref name='S000119930'>Vas AC, et al. (2007) In Vivo Analysis of Chromosome Condensation in Saccharomyces cerevisiae. Mol Biol Cell 18(2):557-68 {{SGDpaper|S000119930}} PMID 17151360</ref><ref name='S000071581'>Cheeseman IM, et al. (2002) Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase Ipl1p. Cell 111(2):163-72 {{SGDpaper|S000071581}} PMID 12408861</ref><ref name='S000066223'>Kang J, et al. (2001) Functional cooperation of Dam1, Ipl1, and the inner centromere protein (INCENP)-related protein Sli15 during chromosome segregation. J Cell Biol 155(5):763-74 |
{{SGDpaper|S000066223}} PMID 11724818</ref> | {{SGDpaper|S000066223}} PMID 11724818</ref> | ||
<br> | <br> | ||
| Line 57: | Line 59: | ||
J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
--> | --> | ||
| + | |||
| + | |||
<protect> | <protect> | ||
Revision as of 08:46, 27 February 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YPL209C |
| Gene name | IPL1 |
| Aliases | PAC15 |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:157592..156489 |
| Primary SGDID | S000006130 |
Description of YPL209C: Aurora kinase involved in regulating kinetochore-microtubule attachments; helps maintain condensed chromosomes during anaphase and early telophase; associates with Sli15p, which promotes Ipl1p association with mitotic spindle[1][2][3]
</protect>
Contents
Community Commentary
About Community Commentary. Please share your knowledge!
Alleles, Strains, and Phenotypes
Point Mutation
Allele: ipl1-321
Strain Background: W303
Phenotype(s): Temperature(Heat) Sensitive
Impairing Ipl1p function restores chromosome attachment in the mtw1-1 mutant , suggesting that Ipl1p promotes the turnover of improper kinetochore-microtubule interactions. [4] [5]
Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [6] [7]
<protect>
References
See Help:References on how to add references
- ↑ Vas AC, et al. (2007) In Vivo Analysis of Chromosome Condensation in Saccharomyces cerevisiae. Mol Biol Cell 18(2):557-68 SGD PMID 17151360
- ↑ Cheeseman IM, et al. (2002) Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase Ipl1p. Cell 111(2):163-72 SGD PMID 12408861
- ↑ Kang J, et al. (2001) Functional cooperation of Dam1, Ipl1, and the inner centromere protein (INCENP)-related protein Sli15 during chromosome segregation. J Cell Biol 155(5):763-74 SGD PMID 11724818
- ↑ Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 SGD PMID 14602074
- ↑ submitted by Benjamin Pinsky on 2004-03-04
- ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ submitted by Jeff Ubersax on 2004-01-29
See Help:Categories on how to add the wiki page for this gene to a Category </protect>
