Difference between revisions of "YPL203W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006124 YPL203W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TPK2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TPK2 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XVI: | + | |nowrap| Chr XVI:166256..167398 |
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000006124 | ||
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<br> | <br> | ||
| − | '''Description of | + | '''Description of YPL203W:''' cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase<ref name='S000042460'>Ordiz I, et al. (1996) Glucose-induced inactivation of isocitrate lyase in Saccharomyces cerevisiae is mediated by the cAMP-dependent protein kinase catalytic subunits Tpk1 and Tpk2. FEBS Lett 385(1-2):43-6 {{SGDpaper|S000042460}} PMID 8641464</ref><ref name='S000043708'>Toda T, et al. (1987) Cloning and characterization of BCY1, a locus encoding a regulatory subunit of the cyclic AMP-dependent protein kinase in Saccharomyces cerevisiae. Mol Cell Biol 7(4):1371-7 {{SGDpaper|S000043708}} PMID 3037314</ref><ref name='S000042132'>Toda T, et al. (1987) Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase. Cell 50(2):277-87 {{SGDpaper|S000042132}} PMID 3036373</ref><ref name='S000131843'>Tudisca V, et al. (2010) Differential localization to cytoplasm, nucleus or P-bodies of yeast PKA subunits under different growth conditions. Eur J Cell Biol 89(4):339-348 |
| − | {{SGDpaper| | + | {{SGDpaper|S000131843}} PMID 19804918</ref> |
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[[Category:Topic:Interactions:Genetic]] | [[Category:Topic:Interactions:Genetic]] | ||
| − | '''Strain Background''': S288C, W303, industrial<br> | + | '''Strain Background''': S288C, W303 (''see [[CommunityW303.html|detailed notes]] from Rodney Rothstein and Stephan Bartsch for the W303 strain used in the study''), industrial<br> |
Genetic interaction with ATF1 [[Category:Genetic Interactions with ATF1]]<br>'''Mutation type(s)''': deletion/partial inactivating | Genetic interaction with ATF1 [[Category:Genetic Interactions with ATF1]]<br>'''Mutation type(s)''': deletion/partial inactivating | ||
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| + | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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| + | <protect> | ||
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| + | ==References== | ||
| + | <!-- REFERENCES ARE AUTOMATICALLY GENERATED. PLEASE DON'T EDIT THIS SECTION--> | ||
| + | {{RefHelp}} | ||
| + | </protect> | ||
<protect> | <protect> | ||
==References== | ==References== | ||
Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YPL203W |
| Gene name | TPK2 |
| Aliases | PKA2, PKA3, YKR1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:166256..167398 |
| Primary SGDID | S000006124 |
Description of YPL203W: cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase[1][2][3][4]
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Community Commentary
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Interactions
Genetic
Strain Background: S288C, W303 (see detailed notes from Rodney Rothstein and Stephan Bartsch for the W303 strain used in the study), industrial
Genetic interaction with ATF1
Mutation type(s): deletion/partial inactivating
ATF1 is transcriptionally induced by glucose and sucrose. This regulation depends on Ras/cAMP/PKA signaling. Long-term expression of ATF1 requires both a fermentable carbon source and a nitrogen source. This regulation depends on FGM signaling. [5] [6]
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References
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- ↑ Ordiz I, et al. (1996) Glucose-induced inactivation of isocitrate lyase in Saccharomyces cerevisiae is mediated by the cAMP-dependent protein kinase catalytic subunits Tpk1 and Tpk2. FEBS Lett 385(1-2):43-6 SGD PMID 8641464
- ↑ Toda T, et al. (1987) Cloning and characterization of BCY1, a locus encoding a regulatory subunit of the cyclic AMP-dependent protein kinase in Saccharomyces cerevisiae. Mol Cell Biol 7(4):1371-7 SGD PMID 3037314
- ↑ Toda T, et al. (1987) Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase. Cell 50(2):277-87 SGD PMID 3036373
- ↑ Tudisca V, et al. (2010) Differential localization to cytoplasm, nucleus or P-bodies of yeast PKA subunits under different growth conditions. Eur J Cell Biol 89(4):339-348 SGD PMID 19804918
- ↑ Verstrepen KJ, et al. (2003) The Saccharomyces cerevisiae alcohol acetyl transferase gene ATF1 is a target of the cAMP/PKA and FGM nutrient-signalling pathways. FEMS Yeast Res 4(3):285-96 SGD PMID 14654433
- ↑ submitted by Kevin J Verstrepen on 2004-03-11
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References
See Help:References on how to add references
See Help:Categories on how to add the wiki page for this gene to a Category </protect>
