Difference between revisions of "YPL152W"
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| − | '''Description of YPL152W:''' Activator of the phosphotyrosyl phosphatase activity of PP2A; regulates G1 phase progression, the osmoresponse | + | '''Description of YPL152W:''' Activator of the phosphotyrosyl phosphatase activity of PP2A,peptidyl-prolyl cis/trans-isomerase; regulates G1 phase progression, the osmoresponse, microtubule dynamics; subunit of the Tap42p-Pph21p-Rrd2p complex<ref name='S000114128'>Jordens J, et al. (2006) The protein phosphatase 2A phosphatase activator is a novel peptidyl-prolyl cis/trans-isomerase. J Biol Chem 281(10):6349-57 {{SGDpaper|S000114128}} PMID 16380387</ref><ref name='S000081883'>Fellner T, et al. (2003) A novel and essential mechanism determining specificity and activity of protein phosphatase 2A (PP2A) in vivo. Genes Dev 17(17):2138-50 {{SGDpaper|S000081883}} PMID 12952889</ref><ref name='S000080636'>Zheng Y and Jiang Y (2005) The yeast phosphotyrosyl phosphatase activator is part of the Tap42-phosphatase complexes. Mol Biol Cell 16(4):2119-27 {{SGDpaper|S000080636}} PMID 15689491</ref><ref name='S000065030'>Van Hoof C, et al. (1998) Functional analysis of conserved domains in the phosphotyrosyl phosphatase activator. Molecular cloning of the homologues from Drosophila melanogaster and Saccharomyces cerevisiae. Biochemistry 37(37):12899-908 {{SGDpaper|S000065030}} PMID 9737869</ref><ref name='S000060029'>Van Hoof C, et al. (2001) The Saccharomyces cerevisiae phosphotyrosyl phosphatase activator proteins are required for a subset of the functions disrupted by protein phosphatase 2A mutations. Exp Cell Res 264(2):372-87 {{SGDpaper|S000060029}} PMID 11262194</ref><ref name='S000059457'>Mitchell DA and Sprague GF Jr (2001) The phosphotyrosyl phosphatase activator, Ncs1p (Rrd1p), functions with Cla4p to regulate the G(2)/M transition in Saccharomyces cerevisiae. Mol Cell Biol 21(2):488-500 {{SGDpaper|S000059457}} PMID 11134337</ref><ref name='S000039114'>Rempola B, et al. (2000) Functional analysis of RRD1 (YIL153w) and RRD2 (YPL152w), which encode two putative activators of the phosphotyrosyl phosphatase activity of PP2A in Saccharomyces cerevisiae. Mol Gen Genet 262(6):1081-92 |
{{SGDpaper|S000039114}} PMID 10660069</ref> | {{SGDpaper|S000039114}} PMID 10660069</ref> | ||
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Revision as of 07:21, 26 February 2009
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| Systematic name | YPL152W |
| Gene name | RRD2 |
| Aliases | YPA2 |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:265027..266103 |
| Primary SGDID | S000006073 |
Description of YPL152W: Activator of the phosphotyrosyl phosphatase activity of PP2A,peptidyl-prolyl cis/trans-isomerase; regulates G1 phase progression, the osmoresponse, microtubule dynamics; subunit of the Tap42p-Pph21p-Rrd2p complex[1][2][3][4][5][6][7]
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References
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- ↑ Jordens J, et al. (2006) The protein phosphatase 2A phosphatase activator is a novel peptidyl-prolyl cis/trans-isomerase. J Biol Chem 281(10):6349-57 SGD PMID 16380387
- ↑ Fellner T, et al. (2003) A novel and essential mechanism determining specificity and activity of protein phosphatase 2A (PP2A) in vivo. Genes Dev 17(17):2138-50 SGD PMID 12952889
- ↑ Zheng Y and Jiang Y (2005) The yeast phosphotyrosyl phosphatase activator is part of the Tap42-phosphatase complexes. Mol Biol Cell 16(4):2119-27 SGD PMID 15689491
- ↑ Van Hoof C, et al. (1998) Functional analysis of conserved domains in the phosphotyrosyl phosphatase activator. Molecular cloning of the homologues from Drosophila melanogaster and Saccharomyces cerevisiae. Biochemistry 37(37):12899-908 SGD PMID 9737869
- ↑ Van Hoof C, et al. (2001) The Saccharomyces cerevisiae phosphotyrosyl phosphatase activator proteins are required for a subset of the functions disrupted by protein phosphatase 2A mutations. Exp Cell Res 264(2):372-87 SGD PMID 11262194
- ↑ Mitchell DA and Sprague GF Jr (2001) The phosphotyrosyl phosphatase activator, Ncs1p (Rrd1p), functions with Cla4p to regulate the G(2)/M transition in Saccharomyces cerevisiae. Mol Cell Biol 21(2):488-500 SGD PMID 11134337
- ↑ Rempola B, et al. (2000) Functional analysis of RRD1 (YIL153w) and RRD2 (YPL152w), which encode two putative activators of the phosphotyrosyl phosphatase activity of PP2A in Saccharomyces cerevisiae. Mol Gen Genet 262(6):1081-92 SGD PMID 10660069
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