Difference between revisions of "YPL082C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006003 YPL082C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MOT1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MOT1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XVI: | + | |nowrap| Chr XVI:404083..398480 |
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000006003 | ||
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| − | '''Description of | + | '''Description of YPL082C:''' Essential abundant protein involved in regulation of transcription, removes Spt15p (TBP) from DNA via its C-terminal ATPase activity, forms a complex with TBP that binds TATA DNA with high affinity but with altered specificity<ref name='S000049440'>Auble DT, et al. (1997) Molecular analysis of the SNF2/SWI2 protein family member MOT1, an ATP-driven enzyme that dissociates TATA-binding protein from DNA. Mol Cell Biol 17(8):4842-51 {{SGDpaper|S000049440}} PMID 9234740</ref><ref name='S000044342'>Collart MA (1996) The NOT, SPT3, and MOT1 genes functionally interact to regulate transcription at core promoters. Mol Cell Biol 16(12):6668-76 {{SGDpaper|S000044342}} PMID 8943321</ref><ref name='S000047968'>Davis JL, et al. (1992) A presumptive helicase (MOT1 gene product) affects gene expression and is required for viability in the yeast Saccharomyces cerevisiae. Mol Cell Biol 12(4):1879-92 {{SGDpaper|S000047968}} PMID 1312673</ref><ref name='S000073835'>Gumbs OH, et al. (2003) High-affinity DNA binding by a Mot1p-TBP complex: implications for TAF-independent transcription. EMBO J 22(12):3131-41 {{SGDpaper|S000073835}} PMID 12805227</ref><ref name='S000064115'>Muldrow TA, et al. (1999) MOT1 can activate basal transcription in vitro by regulating the distribution of TATA binding protein between promoter and nonpromoter sites. Mol Cell Biol 19(4):2835-45 |
| − | {{SGDpaper| | + | {{SGDpaper|S000064115}} PMID 10082549</ref> |
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==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YPL082C |
| Gene name | MOT1 |
| Aliases | BTAF1, BUR3, LPF4 |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:404083..398480 |
| Primary SGDID | S000006003 |
Description of YPL082C: Essential abundant protein involved in regulation of transcription, removes Spt15p (TBP) from DNA via its C-terminal ATPase activity, forms a complex with TBP that binds TATA DNA with high affinity but with altered specificity[1][2][3][4][5]
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References
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- ↑ Auble DT, et al. (1997) Molecular analysis of the SNF2/SWI2 protein family member MOT1, an ATP-driven enzyme that dissociates TATA-binding protein from DNA. Mol Cell Biol 17(8):4842-51 SGD PMID 9234740
- ↑ Collart MA (1996) The NOT, SPT3, and MOT1 genes functionally interact to regulate transcription at core promoters. Mol Cell Biol 16(12):6668-76 SGD PMID 8943321
- ↑ Davis JL, et al. (1992) A presumptive helicase (MOT1 gene product) affects gene expression and is required for viability in the yeast Saccharomyces cerevisiae. Mol Cell Biol 12(4):1879-92 SGD PMID 1312673
- ↑ Gumbs OH, et al. (2003) High-affinity DNA binding by a Mot1p-TBP complex: implications for TAF-independent transcription. EMBO J 22(12):3131-41 SGD PMID 12805227
- ↑ Muldrow TA, et al. (1999) MOT1 can activate basal transcription in vitro by regulating the distribution of TATA binding protein between promoter and nonpromoter sites. Mol Cell Biol 19(4):2835-45 SGD PMID 10082549
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