Difference between revisions of "YPL082C"

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==Community Commentary==
 
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==References==
 
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Revision as of 08:18, 30 January 2007

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Systematic name YPL082C
Gene name MOT1
Aliases BTAF1, BUR3, LPF4
Feature type ORF, Verified
Coordinates Chr XVI:404080..398477


Description of YPL082C: Essential abundant protein involved in regulation of transcription, removes Spt15p (TBP) from DNA via its C-terminal ATPase activity, forms a complex with TBP that binds TATA DNA with high affinity but with altered specificity[1][2][3][4][5]




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Community Commentary

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References

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  1. Gumbs OH, et al. (2003) High-affinity DNA binding by a Mot1p-TBP complex: implications for TAF-independent transcription. EMBO J 22(12):3131-41 SGD PMID 12805227
  2. Muldrow TA, et al. (1999) MOT1 can activate basal transcription in vitro by regulating the distribution of TATA binding protein between promoter and nonpromoter sites. Mol Cell Biol 19(4):2835-45 SGD PMID 10082549
  3. Auble DT, et al. (1997) Molecular analysis of the SNF2/SWI2 protein family member MOT1, an ATP-driven enzyme that dissociates TATA-binding protein from DNA. Mol Cell Biol 17(8):4842-51 SGD PMID 9234740
  4. Davis JL, et al. (1992) A presumptive helicase (MOT1 gene product) affects gene expression and is required for viability in the yeast Saccharomyces cerevisiae. Mol Cell Biol 12(4):1879-92 SGD PMID 1312673
  5. Collart MA (1996) The NOT, SPT3, and MOT1 genes functionally interact to regulate transcription at core promoters. Mol Cell Biol 16(12):6668-76 SGD PMID 8943321

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