Difference between revisions of "YPL008W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005929 YPL008W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CHL1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CHL1 '' | ||
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||''CTF1, LPA9'' | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||''CTF1, LPA9, MCM12'' |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]] | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]] | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XVI: | + | |nowrap| Chr XVI:539385..541970 |
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005929 |
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| − | '''Description of | + | '''Description of YPL008W:''' Probable DNA helicase; involved in sister-chromatid cohesion and genome integrity; interacts with ECO1 and CTF18; mutants are defective in silencing, rDNA recombination, aging and the heat shock response; FANCJ-like helicase family member; mutations in the human homolog, DDX11/ChLR1, cause Warsaw breakage syndrome<ref name='S000086863'>Das SP and Sinha P (2005) The budding yeast protein Chl1p has a role in transcriptional silencing, rDNA recombination, and aging. Biochem Biophys Res Commun 337(1):167-72 {{SGDpaper|S000086863}} PMID 16182251</ref><ref name='S000076406'>Skibbens RV (2004) Chl1p, a DNA helicase-like protein in budding yeast, functions in sister-chromatid cohesion. Genetics 166(1):33-42 {{SGDpaper|S000076406}} PMID 15020404</ref><ref name='S000128804'>Wu Y, et al. (2009) Welcome the family of FANCJ-like helicases to the block of genome stability maintenance proteins. Cell Mol Life Sci 66(7):1209-22 {{SGDpaper|S000128804}} PMID 19099189</ref><ref name='S000147534'>Wu Y, et al. (2011) Biochemical characterization of Warsaw Breakage Syndrome helicase. J Biol Chem () |
| − | {{SGDpaper| | + | {{SGDpaper|S000147534}} PMID 22102414</ref> |
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==Community Commentary== | ==Community Commentary== | ||
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| + | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YPL008W |
| Gene name | CHL1 |
| Aliases | CTF1, LPA9, MCM12 |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:539385..541970 |
| Primary SGDID | S000005929 |
Description of YPL008W: Probable DNA helicase; involved in sister-chromatid cohesion and genome integrity; interacts with ECO1 and CTF18; mutants are defective in silencing, rDNA recombination, aging and the heat shock response; FANCJ-like helicase family member; mutations in the human homolog, DDX11/ChLR1, cause Warsaw breakage syndrome[1][2][3][4]
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Contents
Community Commentary
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References
See Help:References on how to add references
- ↑ Das SP and Sinha P (2005) The budding yeast protein Chl1p has a role in transcriptional silencing, rDNA recombination, and aging. Biochem Biophys Res Commun 337(1):167-72 SGD PMID 16182251
- ↑ Skibbens RV (2004) Chl1p, a DNA helicase-like protein in budding yeast, functions in sister-chromatid cohesion. Genetics 166(1):33-42 SGD PMID 15020404
- ↑ Wu Y, et al. (2009) Welcome the family of FANCJ-like helicases to the block of genome stability maintenance proteins. Cell Mol Life Sci 66(7):1209-22 SGD PMID 19099189
- ↑ Wu Y, et al. (2011) Biochemical characterization of Warsaw Breakage Syndrome helicase. J Biol Chem () SGD PMID 22102414
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