Difference between revisions of "YPL006W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XVI:544628..548140
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|nowrap| Chr XVI:544631..548143
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000005927
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000005927

Revision as of 14:05, 3 February 2011

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Systematic name YPL006W
Gene name NCR1
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:544631..548143
Primary SGDID S000005927


Description of YPL006W: Vacuolar membrane protein that transits through the biosynthetic vacuolar protein sorting pathway, involved in sphingolipid metabolism; glycoprotein and functional orthologue of human Niemann Pick C1 (NPC1) protein[1][2]




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References

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  1. Malathi K, et al. (2004) Mutagenesis of the putative sterol-sensing domain of yeast Niemann Pick C-related protein reveals a primordial role in subcellular sphingolipid distribution. J Cell Biol 164(4):547-56 SGD PMID 14970192
  2. Zhang S, et al. (2004) Ncr1p, the yeast ortholog of mammalian Niemann Pick C1 protein, is dispensable for endocytic transport. Traffic 5(12):1017-30 SGD PMID 15522102

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