Difference between revisions of "YPL004C"

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'''Description of YPL004C:''' Primary component of eisosomes, which are large immobile patch structures at the cell cortex associated with endocytosis, along with Pil1p and Sur7p; null mutants show activation of Pkc1p/Ypk1p stress resistance pathways<ref name='S000114479'>Walther TC, et al. (2006) Eisosomes mark static sites of endocytosis. Nature 439(7079):998-1003 {{SGDpaper|S000114479}} PMID 16496001</ref><ref name='S000076362'>Zhang X, et al. (2004) Pil1p and Lsp1p negatively regulate the 3-phosphoinositide-dependent protein kinase-like kinase Pkh1p and downstream signaling pathways Pkc1p and Ypk1p. J Biol Chem 279(21):22030-8
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'''Description of YPL004C:''' Primary component of eisosomes, which are large immobile patch structures at the cell cortex associated with endocytosis, along with Pil1p and Sur7p; null mutants show activation of Pkc1p/Ypk1p stress resistance pathways<ref name='S000076362'>Zhang X, et al. (2004) Pil1p and Lsp1p negatively regulate the 3-phosphoinositide-dependent protein kinase-like kinase Pkh1p and downstream signaling pathways Pkc1p and Ypk1p. J Biol Chem 279(21):22030-8 {{SGDpaper|S000076362}} PMID 15016821</ref><ref name='S000114479'>Walther TC, et al. (2006) Eisosomes mark static sites of endocytosis. Nature 439(7079):998-1003
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  {{SGDpaper|S000114479}} PMID 16496001</ref>
 
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Revision as of 14:05, 31 March 2009

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Systematic name YPL004C
Gene name LSP1
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:551654..550629
Primary SGDID S000005925


Description of YPL004C: Primary component of eisosomes, which are large immobile patch structures at the cell cortex associated with endocytosis, along with Pil1p and Sur7p; null mutants show activation of Pkc1p/Ypk1p stress resistance pathways[1][2]




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Protein Details

Protein Localization

Protein identified in a purified mitochondrial extract. [3] [4]




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References

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  1. Zhang X, et al. (2004) Pil1p and Lsp1p negatively regulate the 3-phosphoinositide-dependent protein kinase-like kinase Pkh1p and downstream signaling pathways Pkc1p and Ypk1p. J Biol Chem 279(21):22030-8 SGD PMID 15016821
  2. Walther TC, et al. (2006) Eisosomes mark static sites of endocytosis. Nature 439(7079):998-1003 SGD PMID 16496001
  3. Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 SGD PMID 14597615
  4. submitted by Steffen Ohlmeier on 2004-04-08

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