YOR374W

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Systematic name YOR374W
Gene name ALD4
Aliases ALD7
Feature type ORF, Verified
Coordinates Chr XV:1039838..1041397
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Description of YOR374W: Mitochondrial aldehyde dehydrogenase, required for growth on ethanol and conversion of acetaldehyde to acetate; activity is K+ dependent; utilizes NADP+ or NAD+ equally as coenzymes; expression is glucose repressed[1][2]



DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically higher expression in carbon limited chemostat cultures versus carbon excess. [3] [4]


Protein Details

Other Protein Details

Other Topic: Regulated by the diauxic shift (glycerol)

Apart from the overall increase in mitochondrial protein mass this protein is induced after the diauxic shift. [5] [6]


Community Commentary

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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically higher expression in carbon limited chemostat cultures versus carbon excess. [3] [4]


Protein Details

Other Protein Details

Other Topic: Regulated by the diauxic shift (glycerol)

Apart from the overall increase in mitochondrial protein mass this protein is induced after the diauxic shift. [5] [6]


References

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  1. Tessier WD, et al. (1998) Identification and disruption of the gene encoding the K(+)-activated acetaldehyde dehydrogenase of Saccharomyces cerevisiae. FEMS Microbiol Lett 164(1):29-34 SGD PMID 9675847
  2. Navarro-Avino JP, et al. (1999) A proposal for nomenclature of aldehyde dehydrogenases in Saccharomyces cerevisiae and characterization of the stress-inducible ALD2 and ALD3 genes. Yeast 15(10A):829-42 SGD PMID 10407263
  3. 3.0 3.1 Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  4. 4.0 4.1 submitted by Viktor Boer on 2003-07-25
  5. 5.0 5.1 Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 SGD PMID 14597615
  6. 6.0 6.1 submitted by Steffen Ohlmeier on 2004-04-08

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