Difference between revisions of "YOR326W"

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'''Description of YOR326W:''' One of two type V myosin motors (along with MYO4) involved in actin-based transport of cargos; required for the polarized delivery of secretory vesicles, the vacuole, late Golgi elements, peroxisomes, and the mitotic spindle<ref name='S000080705'>Pruyne D, et al. (2004) Mechanisms of polarized growth and organelle segregation in yeast. Annu Rev Cell Dev Biol 20:559-91
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'''Description of YOR326W:''' Type V myosin motor involved in actin-based transport of cargos; required for the polarized delivery of secretory vesicles, the vacuole, late Golgi elements, peroxisomes, and the mitotic spindle; MYO2 has a paralog, MYO4, that arose from the whole genome duplication<ref name='S000113653'>Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 {{SGDpaper|S000113653}} PMID 16169922</ref><ref name='S000080705'>Pruyne D, et al. (2004) Mechanisms of polarized growth and organelle segregation in yeast. Annu Rev Cell Dev Biol 20:559-91
 
  {{SGDpaper|S000080705}} PMID 15473852</ref>
 
  {{SGDpaper|S000080705}} PMID 15473852</ref>
 
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Latest revision as of 14:05, 21 August 2012

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Systematic name YOR326W
Gene name MYO2
Aliases CDC66
Feature type ORF, Verified
Coordinates Chr XV:925721..930445
Primary SGDID S000005853


Description of YOR326W: Type V myosin motor involved in actin-based transport of cargos; required for the polarized delivery of secretory vesicles, the vacuole, late Golgi elements, peroxisomes, and the mitotic spindle; MYO2 has a paralog, MYO4, that arose from the whole genome duplication[1][2]




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Interactions

Physical

Physical interaction with VAC17
Immunoprecipitating Vac17p with sheep anti-Vac17p antibody coprecipitates Myo2p. [3] [4]





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References

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  1. Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 SGD PMID 16169922
  2. Pruyne D, et al. (2004) Mechanisms of polarized growth and organelle segregation in yeast. Annu Rev Cell Dev Biol 20:559-91 SGD PMID 15473852
  3. Tang F, et al. (2003) Regulated degradation of a class V myosin receptor directs movement of the yeast vacuole. Nature 422(6927):87-92 SGD PMID 12594460
  4. submitted by Fusheng Tang on 2003-03-17

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