Difference between revisions of "YOR291W"

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{|{{Prettytable}} align = 'right' width = '200px'
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YOR291W YOR291W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005817 YOR291W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||'' ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''YPK9 ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||'' ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||'' ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Uncharacterized[[Category:ORF]][[Category:ORF, Uncharacterized]]
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XV:861174..865592
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|nowrap| Chr XV:861175..865593
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000005817
 
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'''Description of {{PAGENAME}}:''' Hypothetical protein
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'''Description of YOR291W:''' Vacuolar protein with a possible role in sequestering heavy metals; has similarity to the type V P-type ATPase Spf1p; homolog of human ATP13A2 (PARK9), mutations in which are associated with Parkinson disease and Kufor-Rakeb syndrome<ref name='S000119132'>Catty P, et al. (1997) The complete inventory of the yeast Saccharomyces cerevisiae P-type transport ATPases. FEBS Lett 409(3):325-32 {{SGDpaper|S000119132}} PMID 9224683</ref><ref name='S000070157'>Cronin SR, et al. (2002) Cod1p/Spf1p is a P-type ATPase involved in ER function and Ca2+ homeostasis. J Cell Biol 157(6):1017-28 {{SGDpaper|S000070157}} PMID 12058017</ref><ref name='S000129215'>Gitler AD, et al. (2009) Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity. Nat Genet 41(3):308-15 {{SGDpaper|S000129215}} PMID 19182805</ref><ref name='S000129869'>Schmidt K, et al. (2009) Cd2+, Mn2+, Ni2+ and Se2+ toxicity to Saccharomyces cerevisiae lacking YPK9p the orthologue of human ATP13A2. Biochem Biophys Res Commun 383(2):198-202
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{{SGDpaper|S000129869}} PMID 19345671</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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=== Alleles, Strains, and Phenotypes ===
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[[Category:Topic:Alleles, Strains, and Phenotypes]]
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==== Complete Deletion ====
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[[Category:Topic:Alleles, Strains, and Phenotypes:Complete Deletion]]
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'''Phenotype(s)''': No Phenotype [[Category:Phenotype:No Phenotype]], Viable [[Category:Phenotype:Viable]]
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No obvious phenotypes were detected upon deletion of YOR291w with a KanMX deletion cassette. The deletion was confirmed by PCR. <ref name='S000051798'>Cronin SR, et al. (2000) Regulation of HMG-CoA reductase degradation requires the P-type ATPase Cod1p/Spf1p. J Cell Biol 148(5):915-24 {{SGDpaper|S000051798}} PMID 10704442</ref> <ref name = 'CAset1165-2003-06-13'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=1165 Stephen R. Cronin] on 2003-06-13</ref>
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'''Phenotype(s)''': No Phenotype [[Category:Phenotype:No Phenotype]], Viable [[Category:Phenotype:Viable]]
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No obvious phenotypes were detected upon deletion of YOR291w with a KanMX deletion cassette. The deletion was confirmed by PCR. <ref name='S000051798'>Cronin SR, et al. (2000) Regulation of HMG-CoA reductase degradation requires the P-type ATPase Cod1p/Spf1p. J Cell Biol 148(5):915-24 {{SGDpaper|S000051798}} PMID 10704442</ref> <ref name = 'CAset1165-2003-06-13'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=1165 Stephen R. Cronin] on 2003-06-13</ref>
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 07:45, 23 January 2012

Share your knowledge...Edit this entry! <protect>

Systematic name YOR291W
Gene name YPK9
Aliases
Feature type ORF, Verified
Coordinates Chr XV:861175..865593
Primary SGDID S000005817


Description of YOR291W: Vacuolar protein with a possible role in sequestering heavy metals; has similarity to the type V P-type ATPase Spf1p; homolog of human ATP13A2 (PARK9), mutations in which are associated with Parkinson disease and Kufor-Rakeb syndrome[1][2][3][4]




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Community Commentary

About Community Commentary. Please share your knowledge!

Alleles, Strains, and Phenotypes

Complete Deletion

Phenotype(s): No Phenotype, Viable

No obvious phenotypes were detected upon deletion of YOR291w with a KanMX deletion cassette. The deletion was confirmed by PCR. [5] [6]


Phenotype(s): No Phenotype, Viable

No obvious phenotypes were detected upon deletion of YOR291w with a KanMX deletion cassette. The deletion was confirmed by PCR. [5] [6]





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References

See Help:References on how to add references

  1. Catty P, et al. (1997) The complete inventory of the yeast Saccharomyces cerevisiae P-type transport ATPases. FEBS Lett 409(3):325-32 SGD PMID 9224683
  2. Cronin SR, et al. (2002) Cod1p/Spf1p is a P-type ATPase involved in ER function and Ca2+ homeostasis. J Cell Biol 157(6):1017-28 SGD PMID 12058017
  3. Gitler AD, et al. (2009) Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity. Nat Genet 41(3):308-15 SGD PMID 19182805
  4. Schmidt K, et al. (2009) Cd2+, Mn2+, Ni2+ and Se2+ toxicity to Saccharomyces cerevisiae lacking YPK9p the orthologue of human ATP13A2. Biochem Biophys Res Commun 383(2):198-202 SGD PMID 19345671
  5. 5.0 5.1 Cronin SR, et al. (2000) Regulation of HMG-CoA reductase degradation requires the P-type ATPase Cod1p/Spf1p. J Cell Biol 148(5):915-24 SGD PMID 10704442
  6. 6.0 6.1 submitted by Stephen R. Cronin on 2003-06-13

See Help:Categories on how to add the wiki page for this gene to a Category </protect>