YOR259C
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| Systematic name | YOR259C |
| Gene name | RPT4 |
| Aliases | CRL13, PCS1, SUG2 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:813708..812395 |
Description of YOR259C: One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for spindle pole body duplication; localized mainly to the nucleus throughout the cell cycle[1][2][3][4]
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References
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- ↑ Rubin DM, et al. (1998) Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome. EMBO J 17(17):4909-19 SGD PMID 9724628
- ↑ Russell SJ, et al. (1999) Subcellular localization, stoichiometry, and protein levels of 26 S proteasome subunits in yeast. J Biol Chem 274(31):21943-52 SGD PMID 10419517
- ↑ McDonald HB and Byers B (1997) A proteasome cap subunit required for spindle pole body duplication in yeast. J Cell Biol 137(3):539-53 SGD PMID 9151663
- ↑ Glickman MH, et al. (1998) The regulatory particle of the Saccharomyces cerevisiae proteasome. Mol Cell Biol 18(6):3149-62 SGD PMID 9584156
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