Difference between revisions of "YOR259C"

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'''Description of YOR259C:''' One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for spindle pole body duplication; localized mainly to the nucleus throughout the cell cycle<ref name='S000065027'>Rubin DM, et al. (1998) Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome. EMBO J 17(17):4909-19 {{SGDpaper|S000065027}} PMID 9724628</ref><ref name='S000047509'>Russell SJ, et al. (1999) Subcellular localization, stoichiometry, and protein levels of 26 S proteasome subunits in yeast. J Biol Chem 274(31):21943-52 {{SGDpaper|S000047509}} PMID 10419517</ref><ref name='S000044886'>McDonald HB and Byers B (1997) A proteasome cap subunit required for spindle pole body duplication in yeast. J Cell Biol 137(3):539-53 {{SGDpaper|S000044886}} PMID 9151663</ref><ref name='S000044396'>Glickman MH, et al. (1998) The regulatory particle of the Saccharomyces cerevisiae proteasome. Mol Cell Biol 18(6):3149-62
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'''Description of YOR259C:''' One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for spindle pole body duplication; localized mainly to the nucleus throughout the cell cycle<ref name='S000044396'>Glickman MH, et al. (1998) The regulatory particle of the Saccharomyces cerevisiae proteasome. Mol Cell Biol 18(6):3149-62 {{SGDpaper|S000044396}} PMID 9584156</ref><ref name='S000044886'>McDonald HB and Byers B (1997) A proteasome cap subunit required for spindle pole body duplication in yeast. J Cell Biol 137(3):539-53 {{SGDpaper|S000044886}} PMID 9151663</ref><ref name='S000047509'>Russell SJ, et al. (1999) Subcellular localization, stoichiometry, and protein levels of 26 S proteasome subunits in yeast. J Biol Chem 274(31):21943-52 {{SGDpaper|S000047509}} PMID 10419517</ref><ref name='S000065027'>Rubin DM, et al. (1998) Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome. EMBO J 17(17):4909-19
  {{SGDpaper|S000044396}} PMID 9584156</ref>
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  {{SGDpaper|S000065027}} PMID 9724628</ref>
 
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Revision as of 14:05, 31 March 2009

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Systematic name YOR259C
Gene name RPT4
Aliases CRL13, PCS1, SUG2
Feature type ORF, Verified
Coordinates Chr XV:813708..812395
Primary SGDID S000005785


Description of YOR259C: One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for spindle pole body duplication; localized mainly to the nucleus throughout the cell cycle[1][2][3][4]




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References

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  1. Glickman MH, et al. (1998) The regulatory particle of the Saccharomyces cerevisiae proteasome. Mol Cell Biol 18(6):3149-62 SGD PMID 9584156
  2. McDonald HB and Byers B (1997) A proteasome cap subunit required for spindle pole body duplication in yeast. J Cell Biol 137(3):539-53 SGD PMID 9151663
  3. Russell SJ, et al. (1999) Subcellular localization, stoichiometry, and protein levels of 26 S proteasome subunits in yeast. J Biol Chem 274(31):21943-52 SGD PMID 10419517
  4. Rubin DM, et al. (1998) Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome. EMBO J 17(17):4909-19 SGD PMID 9724628

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