Difference between revisions of "YOR205C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''GEP3 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''GEP3 ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''AIM40, FMP38, LRC5''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''AIM40, FMP38, LRC5, MTG3''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
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'''Description of YOR205C:''' Protein of unknown function; null mutant is defective in respiration and interacts synthetically with prohibitin (phb1); the authentic, non-tagged protein is detected in purified mitochondria in high-throughput studies<ref name='S000129658'>Hess DC, et al. (2009) Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis. PLoS Genet 5(3):e1000407 {{SGDpaper|S000129658}} PMID 19300474</ref><ref name='S000129376'>Osman C, et al. (2009) The genetic interactome of prohibitins: coordinated control of cardiolipin and phosphatidylethanolamine by conserved regulators in mitochondria. J Cell Biol 184(4):583-96 {{SGDpaper|S000129376}} PMID 19221197</ref><ref name='S000117178'>Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54
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'''Description of YOR205C:''' Protein required for mitochondrial ribosome small subunit biogenesis; null mutant is defective in respiration and in maturation of 15S rRNA; protein is localized to the mitochondrial inner membrane; null mutant interacts synthetically with prohibitin (phb1)<ref name='S000129658'>Hess DC, et al. (2009) Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis. PLoS Genet 5(3):e1000407 {{SGDpaper|S000129658}} PMID 19300474</ref><ref name='S000129376'>Osman C, et al. (2009) The genetic interactome of prohibitins: coordinated control of cardiolipin and phosphatidylethanolamine by conserved regulators in mitochondria. J Cell Biol 184(4):583-96 {{SGDpaper|S000129376}} PMID 19221197</ref><ref name='S000149537'>Paul MF, et al. (2012) The putative GTPase encoded by MTG3 functions in a novel pathway for regulating assembly of the small subunit of yeast mitochondrial ribosomes. J Biol Chem ()
  {{SGDpaper|S000117178}} PMID 16823961</ref>
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  {{SGDpaper|S000149537}} PMID 22621929</ref>
 
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Latest revision as of 14:05, 11 June 2012

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Systematic name YOR205C
Gene name GEP3
Aliases AIM40, FMP38, LRC5, MTG3
Feature type ORF, Verified
Coordinates Chr XV:727234..725564
Primary SGDID S000005731


Description of YOR205C: Protein required for mitochondrial ribosome small subunit biogenesis; null mutant is defective in respiration and in maturation of 15S rRNA; protein is localized to the mitochondrial inner membrane; null mutant interacts synthetically with prohibitin (phb1)[1][2][3]




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References

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  1. Hess DC, et al. (2009) Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis. PLoS Genet 5(3):e1000407 SGD PMID 19300474
  2. Osman C, et al. (2009) The genetic interactome of prohibitins: coordinated control of cardiolipin and phosphatidylethanolamine by conserved regulators in mitochondria. J Cell Biol 184(4):583-96 SGD PMID 19221197
  3. Paul MF, et al. (2012) The putative GTPase encoded by MTG3 functions in a novel pathway for regulating assembly of the small subunit of yeast mitochondrial ribosomes. J Biol Chem () SGD PMID 22621929

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