Difference between revisions of "YOR175C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YOR175C YOR175C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005701 YOR175C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||'' ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''ALE1 ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||'' ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''LCA1, LPT1, SLC4''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XV:661675..659816
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|nowrap| Chr XV:661674..659815
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000005701
 
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'''Description of {{PAGENAME}}:''' Protein of unknown function that may interact with ribosomes, based on co-purification experiments; member of the MBOAT family of putative membrane-bound O-acyltransferases<ref name='S000115662'>Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 {{SGDpaper|S000115662}} PMID 16702403</ref><ref name='S000081341'>Hofmann K (2000) A superfamily of membrane-bound O-acyltransferases with implications for wnt signaling. Trends Biochem Sci 25(3):111-2
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'''Description of YOR175C:''' Broad-specificity lysophospholipid acyltransferase, part of MBOAT family of membrane-bound O-acyltransferases; key component of Lands cycle; may have role in fatty acid exchange at sn-2 position of mature glycerophospholipids<ref name='S000123744'>Benghezal M, et al. (2007) SLC1 and SLC4 Encode Partially Redundant Acyl-Coenzyme A 1-Acylglycerol-3-phosphate O-Acyltransferases of Budding Yeast. J Biol Chem 282(42):30845-55 {{SGDpaper|S000123744}} PMID 17675291</ref><ref name='S000124731'>Chen Q, et al. (2007) The yeast acylglycerol acyltransferase LCA1 is a key component of Lands cycle for phosphatidylcholine turnover. FEBS Lett 581(28):5511-6 {{SGDpaper|S000124731}} PMID 17996202</ref><ref name='S000123926'>Jain S, et al. (2007) Identification of a Novel Lysophospholipid Acyltransferase in Saccharomyces cerevisiae. J Biol Chem 282(42):30562-9 {{SGDpaper|S000123926}} PMID 17726007</ref><ref name='S000123546'>Riekhof WR, et al. (2007) Identification and characterization of the major lysophosphatidylethanolamine acyltransferase in Saccharomyces cerevisiae. J Biol Chem 282(39):28344-52 {{SGDpaper|S000123546}} PMID 17652094</ref><ref name='S000124469'>Riekhof WR, et al. (2007) Lysophosphatidylcholine metabolism in Saccharomyces cerevisiae: the role of P-type ATPases in transport and a broad specificity acyltransferase in acylation. J Biol Chem 282(51):36853-61
  {{SGDpaper|S000081341}} PMID 10694878</ref>
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  {{SGDpaper|S000124469}} PMID 17951629</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YOR175C
Gene name ALE1
Aliases LCA1, LPT1, SLC4
Feature type ORF, Verified
Coordinates Chr XV:661674..659815
Primary SGDID S000005701


Description of YOR175C: Broad-specificity lysophospholipid acyltransferase, part of MBOAT family of membrane-bound O-acyltransferases; key component of Lands cycle; may have role in fatty acid exchange at sn-2 position of mature glycerophospholipids[1][2][3][4][5]




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References

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  1. Benghezal M, et al. (2007) SLC1 and SLC4 Encode Partially Redundant Acyl-Coenzyme A 1-Acylglycerol-3-phosphate O-Acyltransferases of Budding Yeast. J Biol Chem 282(42):30845-55 SGD PMID 17675291
  2. Chen Q, et al. (2007) The yeast acylglycerol acyltransferase LCA1 is a key component of Lands cycle for phosphatidylcholine turnover. FEBS Lett 581(28):5511-6 SGD PMID 17996202
  3. Jain S, et al. (2007) Identification of a Novel Lysophospholipid Acyltransferase in Saccharomyces cerevisiae. J Biol Chem 282(42):30562-9 SGD PMID 17726007
  4. Riekhof WR, et al. (2007) Identification and characterization of the major lysophosphatidylethanolamine acyltransferase in Saccharomyces cerevisiae. J Biol Chem 282(39):28344-52 SGD PMID 17652094
  5. Riekhof WR, et al. (2007) Lysophosphatidylcholine metabolism in Saccharomyces cerevisiae: the role of P-type ATPases in transport and a broad specificity acyltransferase in acylation. J Biol Chem 282(51):36853-61 SGD PMID 17951629

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