Difference between revisions of "YOR173W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005699 YOR173W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005699 YOR173W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''DCS2 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''DCS2 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XV:657265..658326
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|nowrap| Chr XV:657264..658325
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000005699
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000005699
 
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'''Description of YOR173W:''' Non-essential, stress induced regulatory protein containing a HIT (histidine triad) motif; modulates m7G-oligoribonucleotide metabolism; inhibits Dcs1p; regulated by Msn2p, Msn4p, and the Ras-cAMP-cAPK signaling pathway, similar to Dcs1p.<ref name='S000046583'>Tadi D, et al. (1999) Selection of genes repressed by cAMP that are induced by nutritional limitation in Saccharomyces cerevisiae. Yeast 15(16):1733-45 {{SGDpaper|S000046583}} PMID 10590462</ref><ref name='S000076812'>Malys N, et al. (2004) The 'scavenger' m7GpppX pyrophosphatase activity of Dcs1 modulates nutrient-induced responses in yeast. Nucleic Acids Res 32(12):3590-600 {{SGDpaper|S000076812}} PMID 15240832</ref><ref name='S000071470'>Liu H, et al. (2002) The scavenger mRNA decapping enzyme DcpS is a member of the HIT family of pyrophosphatases. EMBO J 21(17):4699-708 {{SGDpaper|S000071470}} PMID 12198172</ref><ref name='S000118884'>Malys N and McCarthy JE (2006) Dcs2, a novel stress-induced modulator of m7GpppX pyrophosphatase activity that locates to P bodies. J Mol Biol 363(2):370-82
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'''Description of YOR173W:''' Non-essential, stress induced regulatory protein; modulates m7G-oligoribonucleotide metabolism; inhibits Dcs1p; regulated by Msn2p, Msn4p, and the Ras-cAMP-cAPK signaling pathway; mutant has increased aneuploidy tolerance<ref name='S000071470'>Liu H, et al. (2002) The scavenger mRNA decapping enzyme DcpS is a member of the HIT family of pyrophosphatases. EMBO J 21(17):4699-708 {{SGDpaper|S000071470}} PMID 12198172</ref><ref name='S000118884'>Malys N and McCarthy JE (2006) Dcs2, a novel stress-induced modulator of m7GpppX pyrophosphatase activity that locates to P bodies. J Mol Biol 363(2):370-82 {{SGDpaper|S000118884}} PMID 16963086</ref><ref name='S000076812'>Malys N, et al. (2004) The 'scavenger' m7GpppX pyrophosphatase activity of Dcs1 modulates nutrient-induced responses in yeast. Nucleic Acids Res 32(12):3590-600 {{SGDpaper|S000076812}} PMID 15240832</ref><ref name='S000046583'>Tadi D, et al. (1999) Selection of genes repressed by cAMP that are induced by nutritional limitation in Saccharomyces cerevisiae. Yeast 15(16):1733-45 {{SGDpaper|S000046583}} PMID 10590462</ref><ref name='S000136872'>Torres EM, et al. (2010) Identification of aneuploidy-tolerating mutations. Cell 143(1):71-83
  {{SGDpaper|S000118884}} PMID 16963086</ref>
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  {{SGDpaper|S000136872}} PMID 20850176</ref>
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YOR173W
Gene name DCS2
Aliases
Feature type ORF, Verified
Coordinates Chr XV:657264..658325
Primary SGDID S000005699


Description of YOR173W: Non-essential, stress induced regulatory protein; modulates m7G-oligoribonucleotide metabolism; inhibits Dcs1p; regulated by Msn2p, Msn4p, and the Ras-cAMP-cAPK signaling pathway; mutant has increased aneuploidy tolerance[1][2][3][4][5]




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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically lower expression in sulfur limited chemostat cultures versus sulfur excess. [6] [7]





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References

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  1. Liu H, et al. (2002) The scavenger mRNA decapping enzyme DcpS is a member of the HIT family of pyrophosphatases. EMBO J 21(17):4699-708 SGD PMID 12198172
  2. Malys N and McCarthy JE (2006) Dcs2, a novel stress-induced modulator of m7GpppX pyrophosphatase activity that locates to P bodies. J Mol Biol 363(2):370-82 SGD PMID 16963086
  3. Malys N, et al. (2004) The 'scavenger' m7GpppX pyrophosphatase activity of Dcs1 modulates nutrient-induced responses in yeast. Nucleic Acids Res 32(12):3590-600 SGD PMID 15240832
  4. Tadi D, et al. (1999) Selection of genes repressed by cAMP that are induced by nutritional limitation in Saccharomyces cerevisiae. Yeast 15(16):1733-45 SGD PMID 10590462
  5. Torres EM, et al. (2010) Identification of aneuploidy-tolerating mutations. Cell 143(1):71-83 SGD PMID 20850176
  6. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  7. submitted by Viktor Boer on 2003-07-25

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