Difference between revisions of "YOR153W"
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| − | '''Description of YOR153W:''' Plasma membrane ATP-binding cassette (ABC) transporter, multidrug transporter actively regulated by Pdr1p; also involved in steroid transport, cation resistance, and cellular detoxification during exponential growth | + | '''Description of YOR153W:''' Plasma membrane ATP-binding cassette (ABC) transporter, multidrug transporter actively regulated by Pdr1p; also involved in steroid transport, cation resistance, and cellular detoxification during exponential growth<ref name='S000042040'>Balzi E, et al. (1994) PDR5, a novel yeast multidrug resistance conferring transporter controlled by the transcription regulator PDR1. J Biol Chem 269(3):2206-14 {{SGDpaper|S000042040}} PMID 8294477</ref><ref name='S000042972'>Bissinger PH and Kuchler K (1994) Molecular cloning and expression of the Saccharomyces cerevisiae STS1 gene product. A yeast ABC transporter conferring mycotoxin resistance. J Biol Chem 269(6):4180-6 {{SGDpaper|S000042972}} PMID 8307980</ref><ref name='S000052729'>Egner R and Kuchler K (1996) The yeast multidrug transporter Pdr5 of the plasma membrane is ubiquitinated prior to endocytosis and degradation in the vacuole. FEBS Lett 378(2):177-81 {{SGDpaper|S000052729}} PMID 8549828</ref><ref name='S000043769'>Egner R, et al. (1995) Endocytosis and vacuolar degradation of the plasma membrane-localized Pdr5 ATP-binding cassette multidrug transporter in Saccharomyces cerevisiae. Mol Cell Biol 15(11):5879-87 {{SGDpaper|S000043769}} PMID 7565740</ref><ref name='S000069994'>Emter R, et al. (2002) ERG6 and PDR5 regulate small lipophilic drug accumulation in yeast cells via distinct mechanisms. FEBS Lett 521(1-3):57-61 {{SGDpaper|S000069994}} PMID 12067726</ref><ref name='S000040660'>Mahe Y, et al. (1996) The ATP binding cassette transporters Pdr5 and Snq2 of Saccharomyces cerevisiae can mediate transport of steroids in vivo. J Biol Chem 271(41):25167-72 {{SGDpaper|S000040660}} PMID 8810273</ref><ref name='S000075843'>Mamnun YM, et al. (2004) Expression regulation of the yeast PDR5 ATP-binding cassette (ABC) transporter suggests a role in cellular detoxification during the exponential growth phase. FEBS Lett 559(1-3):111-7 {{SGDpaper|S000075843}} PMID 14960317</ref><ref name='S000042556'>Miyahara K, et al. (1996) The involvement of the Saccharomyces cerevisiae multidrug resistance transporters Pdr5p and Snq2p in cation resistance. FEBS Lett 399(3):317-20 {{SGDpaper|S000042556}} PMID 8985171</ref><ref name='S000060194'>Rogers B, et al. (2001) The pleitropic drug ABC transporters from Saccharomyces cerevisiae. J Mol Microbiol Biotechnol 3(2):207-14 |
| − | {{SGDpaper| | + | {{SGDpaper|S000060194}} PMID 11321575</ref> |
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Revision as of 14:05, 25 February 2010
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| Systematic name | YOR153W |
| Gene name | PDR5 |
| Aliases | LEM1, STS1, YDR1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:619841..624376 |
| Primary SGDID | S000005679 |
Description of YOR153W: Plasma membrane ATP-binding cassette (ABC) transporter, multidrug transporter actively regulated by Pdr1p; also involved in steroid transport, cation resistance, and cellular detoxification during exponential growth[1][2][3][4][5][6][7][8][9]
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References
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- ↑ Balzi E, et al. (1994) PDR5, a novel yeast multidrug resistance conferring transporter controlled by the transcription regulator PDR1. J Biol Chem 269(3):2206-14 SGD PMID 8294477
- ↑ Bissinger PH and Kuchler K (1994) Molecular cloning and expression of the Saccharomyces cerevisiae STS1 gene product. A yeast ABC transporter conferring mycotoxin resistance. J Biol Chem 269(6):4180-6 SGD PMID 8307980
- ↑ Egner R and Kuchler K (1996) The yeast multidrug transporter Pdr5 of the plasma membrane is ubiquitinated prior to endocytosis and degradation in the vacuole. FEBS Lett 378(2):177-81 SGD PMID 8549828
- ↑ Egner R, et al. (1995) Endocytosis and vacuolar degradation of the plasma membrane-localized Pdr5 ATP-binding cassette multidrug transporter in Saccharomyces cerevisiae. Mol Cell Biol 15(11):5879-87 SGD PMID 7565740
- ↑ Emter R, et al. (2002) ERG6 and PDR5 regulate small lipophilic drug accumulation in yeast cells via distinct mechanisms. FEBS Lett 521(1-3):57-61 SGD PMID 12067726
- ↑ Mahe Y, et al. (1996) The ATP binding cassette transporters Pdr5 and Snq2 of Saccharomyces cerevisiae can mediate transport of steroids in vivo. J Biol Chem 271(41):25167-72 SGD PMID 8810273
- ↑ Mamnun YM, et al. (2004) Expression regulation of the yeast PDR5 ATP-binding cassette (ABC) transporter suggests a role in cellular detoxification during the exponential growth phase. FEBS Lett 559(1-3):111-7 SGD PMID 14960317
- ↑ Miyahara K, et al. (1996) The involvement of the Saccharomyces cerevisiae multidrug resistance transporters Pdr5p and Snq2p in cation resistance. FEBS Lett 399(3):317-20 SGD PMID 8985171
- ↑ Rogers B, et al. (2001) The pleitropic drug ABC transporters from Saccharomyces cerevisiae. J Mol Microbiol Biotechnol 3(2):207-14 SGD PMID 11321575
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