Difference between revisions of "YOR136W"
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| − | '''Description of YOR136W:''' Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which catalyzes the oxidation of isocitrate to alpha-ketoglutarate in the TCA cycle<ref name='S000044854'>Cupp JR and McAlister-Henn L (1991) NAD(+)-dependent isocitrate dehydrogenase. Cloning, nucleotide sequence, and disruption of the IDH2 gene from Saccharomyces cerevisiae. J Biol Chem 266(33):22199-205 | + | '''Description of YOR136W:''' Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which catalyzes the oxidation of isocitrate to alpha-ketoglutarate in the TCA cycle; phosphorylated<ref name='S000123951'>Reinders J, et al. (2007) Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics 6(11):1896-906 {{SGDpaper|S000123951}} PMID 17761666</ref><ref name='S000044854'>Cupp JR and McAlister-Henn L (1991) NAD(+)-dependent isocitrate dehydrogenase. Cloning, nucleotide sequence, and disruption of the IDH2 gene from Saccharomyces cerevisiae. J Biol Chem 266(33):22199-205 |
{{SGDpaper|S000044854}} PMID 1939242</ref> | {{SGDpaper|S000044854}} PMID 1939242</ref> | ||
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Revision as of 07:21, 26 February 2009
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| Systematic name | YOR136W |
| Gene name | IDH2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:580251..581360 |
| Primary SGDID | S000005662 |
Description of YOR136W: Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which catalyzes the oxidation of isocitrate to alpha-ketoglutarate in the TCA cycle; phosphorylated[1][2]
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Protein Details
Other Protein Details
Other Topic: Regulated by the diauxic shift (glycerol)
Apart form the overall increase in mitochondrial protein mass after the diauxic shift this protein remains unchanged after the diauxic shift. [3] [4]
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References
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- ↑ Reinders J, et al. (2007) Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics 6(11):1896-906 SGD PMID 17761666
- ↑ Cupp JR and McAlister-Henn L (1991) NAD(+)-dependent isocitrate dehydrogenase. Cloning, nucleotide sequence, and disruption of the IDH2 gene from Saccharomyces cerevisiae. J Biol Chem 266(33):22199-205 SGD PMID 1939242
- ↑ Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 SGD PMID 14597615
- ↑ submitted by Steffen Ohlmeier on 2004-04-08
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