Difference between revisions of "YOR123C"

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'''Description of YOR123C:''' Component of the Paf1 complex, which associates with RNA polymerase II and is involved in histone methylation<ref name='S000074318'>Wood A, et al. (2003) The Paf1 complex is essential for histone monoubiquitination by the Rad6-Bre1 complex, which signals for histone methylation by COMPASS and Dot1p. J Biol Chem 278(37):34739-42 {{SGDpaper|S000074318}} PMID 12876294</ref><ref name='S000073147'>Krogan NJ, et al. (2003) The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylation. Mol Cell 11(3):721-9 {{SGDpaper|S000073147}} PMID 12667454</ref><ref name='S000071874'>Betz JL, et al. (2002) Phenotypic analysis of Paf1/RNA polymerase II complex mutations reveals connections to cell cycle regulation, protein synthesis, and lipid and nucleic acid metabolism. Mol Genet Genomics 268(2):272-85 {{SGDpaper|S000071874}} PMID 12395202</ref><ref name='S000069696'>Mueller CL and Jaehning JA (2002) Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex. Mol Cell Biol 22(7):1971-80
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'''Description of YOR123C:''' Component of the Paf1 complex, which associates with RNA polymerase II and is involved in histone methylation; plays a role in regulating Ty1 transposition<ref name='S000125260'>Nyswaner KM, et al. (2008) Chromatin-associated genes protect the yeast genome from ty1 insertional mutagenesis. Genetics 178(1):197-214 {{SGDpaper|S000125260}} PMID 18202368</ref><ref name='S000074318'>Wood A, et al. (2003) The Paf1 complex is essential for histone monoubiquitination by the Rad6-Bre1 complex, which signals for histone methylation by COMPASS and Dot1p. J Biol Chem 278(37):34739-42 {{SGDpaper|S000074318}} PMID 12876294</ref><ref name='S000073147'>Krogan NJ, et al. (2003) The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylation. Mol Cell 11(3):721-9 {{SGDpaper|S000073147}} PMID 12667454</ref><ref name='S000071874'>Betz JL, et al. (2002) Phenotypic analysis of Paf1/RNA polymerase II complex mutations reveals connections to cell cycle regulation, protein synthesis, and lipid and nucleic acid metabolism. Mol Genet Genomics 268(2):272-85 {{SGDpaper|S000071874}} PMID 12395202</ref><ref name='S000069696'>Mueller CL and Jaehning JA (2002) Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex. Mol Cell Biol 22(7):1971-80
 
  {{SGDpaper|S000069696}} PMID 11884586</ref>
 
  {{SGDpaper|S000069696}} PMID 11884586</ref>
 
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Revision as of 07:21, 26 February 2009

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Systematic name YOR123C
Gene name LEO1
Aliases
Feature type ORF, Verified
Coordinates Chr XV:554571..553177
Primary SGDID S000005649


Description of YOR123C: Component of the Paf1 complex, which associates with RNA polymerase II and is involved in histone methylation; plays a role in regulating Ty1 transposition[1][2][3][4][5]




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References

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  1. Nyswaner KM, et al. (2008) Chromatin-associated genes protect the yeast genome from ty1 insertional mutagenesis. Genetics 178(1):197-214 SGD PMID 18202368
  2. Wood A, et al. (2003) The Paf1 complex is essential for histone monoubiquitination by the Rad6-Bre1 complex, which signals for histone methylation by COMPASS and Dot1p. J Biol Chem 278(37):34739-42 SGD PMID 12876294
  3. Krogan NJ, et al. (2003) The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylation. Mol Cell 11(3):721-9 SGD PMID 12667454
  4. Betz JL, et al. (2002) Phenotypic analysis of Paf1/RNA polymerase II complex mutations reveals connections to cell cycle regulation, protein synthesis, and lipid and nucleic acid metabolism. Mol Genet Genomics 268(2):272-85 SGD PMID 12395202
  5. Mueller CL and Jaehning JA (2002) Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex. Mol Cell Biol 22(7):1971-80 SGD PMID 11884586

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