Difference between revisions of "YOR089C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YOR089C YOR089C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005615 YOR089C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''VPS21 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''VPS21 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XV:490830..490198
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|nowrap| Chr XV:490828..490196
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000005615
 
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'''Description of {{PAGENAME}}:''' GTPase required for transport during endocytosis and for correct sorting of vacuolar hydrolases; localized in endocytic intermediates; detected in mitochondria; geranylgeranylation required for membrane association; mammalian Rab5 homolog<ref name='S000075100'>Sickmann A, et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12 {{SGDpaper|S000075100}} PMID 14576278</ref><ref name='S000070388'>Neukamm B, et al. (2002) Endocytosis is involved in DNA uptake in yeast. Biochim Biophys Acta 1572(1):67-76 {{SGDpaper|S000070388}} PMID 12204334</ref><ref name='S000042833'>Singer-Kruger B, et al. (1994) Role of three rab5-like GTPases, Ypt51p, Ypt52p, and Ypt53p, in the endocytic and vacuolar protein sorting pathways of yeast. J Cell Biol 125(2):283-98 {{SGDpaper|S000042833}} PMID 8163546</ref><ref name='S000041251'>Horazdovsky BF, et al. (1994) VPS21 encodes a rab5-like GTP binding protein that is required for the sorting of yeast vacuolar proteins. EMBO J 13(6):1297-309
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'''Description of YOR089C:''' Rab family GTPase required for endocytic transport and for sorting of vacuolar hydrolases; localized in endocytic intermediates; detected in mitochondria; geranylgeranylation required for membrane association; mammalian Rab5 homolog<ref name='S000041251'>Horazdovsky BF, et al. (1994) VPS21 encodes a rab5-like GTP binding protein that is required for the sorting of yeast vacuolar proteins. EMBO J 13(6):1297-309 {{SGDpaper|S000041251}} PMID 8137814</ref><ref name='S000070388'>Neukamm B, et al. (2002) Endocytosis is involved in DNA uptake in yeast. Biochim Biophys Acta 1572(1):67-76 {{SGDpaper|S000070388}} PMID 12204334</ref><ref name='S000075100'>Sickmann A, et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12 {{SGDpaper|S000075100}} PMID 14576278</ref><ref name='S000042833'>Singer-Kruger B, et al. (1994) Role of three rab5-like GTPases, Ypt51p, Ypt52p, and Ypt53p, in the endocytic and vacuolar protein sorting pathways of yeast. J Cell Biol 125(2):283-98
  {{SGDpaper|S000041251}} PMID 8137814</ref>
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  {{SGDpaper|S000042833}} PMID 8163546</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
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<!--
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Latest revision as of 07:45, 23 January 2012

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Systematic name YOR089C
Gene name VPS21
Aliases VPS12, VPT12, YPT21, YPT51
Feature type ORF, Verified
Coordinates Chr XV:490828..490196
Primary SGDID S000005615


Description of YOR089C: Rab family GTPase required for endocytic transport and for sorting of vacuolar hydrolases; localized in endocytic intermediates; detected in mitochondria; geranylgeranylation required for membrane association; mammalian Rab5 homolog[1][2][3][4]




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References

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  1. Horazdovsky BF, et al. (1994) VPS21 encodes a rab5-like GTP binding protein that is required for the sorting of yeast vacuolar proteins. EMBO J 13(6):1297-309 SGD PMID 8137814
  2. Neukamm B, et al. (2002) Endocytosis is involved in DNA uptake in yeast. Biochim Biophys Acta 1572(1):67-76 SGD PMID 12204334
  3. Sickmann A, et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12 SGD PMID 14576278
  4. Singer-Kruger B, et al. (1994) Role of three rab5-like GTPases, Ypt51p, Ypt52p, and Ypt53p, in the endocytic and vacuolar protein sorting pathways of yeast. J Cell Biol 125(2):283-98 SGD PMID 8163546

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