Difference between revisions of "YOR089C"

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'''Description of YOR089C:''' GTPase required for transport during endocytosis and for correct sorting of vacuolar hydrolases; localized in endocytic intermediates; detected in mitochondria; geranylgeranylation required for membrane association; mammalian Rab5 homolog<ref name='S000041251'>Horazdovsky BF, et al. (1994) VPS21 encodes a rab5-like GTP binding protein that is required for the sorting of yeast vacuolar proteins. EMBO J 13(6):1297-309 {{SGDpaper|S000041251}} PMID 8137814</ref><ref name='S000042833'>Singer-Kruger B, et al. (1994) Role of three rab5-like GTPases, Ypt51p, Ypt52p, and Ypt53p, in the endocytic and vacuolar protein sorting pathways of yeast. J Cell Biol 125(2):283-98 {{SGDpaper|S000042833}} PMID 8163546</ref><ref name='S000070388'>Neukamm B, et al. (2002) Endocytosis is involved in DNA uptake in yeast. Biochim Biophys Acta 1572(1):67-76 {{SGDpaper|S000070388}} PMID 12204334</ref><ref name='S000075100'>Sickmann A, et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12
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'''Description of YOR089C:''' GTPase required for transport during endocytosis and for correct sorting of vacuolar hydrolases; localized in endocytic intermediates; detected in mitochondria; geranylgeranylation required for membrane association; mammalian Rab5 homolog<ref name='S000041251'>Horazdovsky BF, et al. (1994) VPS21 encodes a rab5-like GTP binding protein that is required for the sorting of yeast vacuolar proteins. EMBO J 13(6):1297-309 {{SGDpaper|S000041251}} PMID 8137814</ref><ref name='S000070388'>Neukamm B, et al. (2002) Endocytosis is involved in DNA uptake in yeast. Biochim Biophys Acta 1572(1):67-76 {{SGDpaper|S000070388}} PMID 12204334</ref><ref name='S000075100'>Sickmann A, et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12 {{SGDpaper|S000075100}} PMID 14576278</ref><ref name='S000042833'>Singer-Kruger B, et al. (1994) Role of three rab5-like GTPases, Ypt51p, Ypt52p, and Ypt53p, in the endocytic and vacuolar protein sorting pathways of yeast. J Cell Biol 125(2):283-98
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  {{SGDpaper|S000042833}} PMID 8163546</ref>
 
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Revision as of 14:05, 25 February 2010

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Systematic name YOR089C
Gene name VPS21
Aliases VPS12, VPT12, YPT21, YPT51
Feature type ORF, Verified
Coordinates Chr XV:490830..490198
Primary SGDID S000005615


Description of YOR089C: GTPase required for transport during endocytosis and for correct sorting of vacuolar hydrolases; localized in endocytic intermediates; detected in mitochondria; geranylgeranylation required for membrane association; mammalian Rab5 homolog[1][2][3][4]




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References

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  1. Horazdovsky BF, et al. (1994) VPS21 encodes a rab5-like GTP binding protein that is required for the sorting of yeast vacuolar proteins. EMBO J 13(6):1297-309 SGD PMID 8137814
  2. Neukamm B, et al. (2002) Endocytosis is involved in DNA uptake in yeast. Biochim Biophys Acta 1572(1):67-76 SGD PMID 12204334
  3. Sickmann A, et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12 SGD PMID 14576278
  4. Singer-Kruger B, et al. (1994) Role of three rab5-like GTPases, Ypt51p, Ypt52p, and Ypt53p, in the endocytic and vacuolar protein sorting pathways of yeast. J Cell Biol 125(2):283-98 SGD PMID 8163546

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