YOR027W
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| Systematic name | YOR027W | |
| Gene name | STI1 | |
| Aliases | ||
| Feature type | ORF, Verified | |
| Coordinates | Chr XV:381053..382822 | |
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Description of YOR027W: Hsp90 cochaperone, interacts with the Ssa group of the cytosolic Hsp70 chaperones; activates the ATPase activity of Ssa1p; homolog of mammalian Hop protein[1][2][3][4]
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References
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- ↑ Wegele H, et al. (2003) Sti1 is a novel activator of the Ssa proteins. J Biol Chem 278(28):25970-6 SGD PMID 12716905
- ↑ Richter K, et al. (2003) Sti1 is a non-competitive inhibitor of the Hsp90 ATPase. Binding prevents the N-terminal dimerization reaction during the atpase cycle. J Biol Chem 278(12):10328-33 SGD PMID 12525481
- ↑ Chang HC, et al. (1997) In vivo analysis of the Hsp90 cochaperone Sti1 (p60). Mol Cell Biol 17(1):318-25 SGD PMID 8972212
- ↑ Nicolet CM and Craig EA (1989) Isolation and characterization of STI1, a stress-inducible gene from Saccharomyces cerevisiae. Mol Cell Biol 9(9):3638-46 SGD PMID 2674681
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