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Systematic name YOL158C
Gene name ENB1
Aliases ARN4
Feature type ORF, Verified
Coordinates Chr XV:21311..19491
Primary SGDID S000005518

Description of YOL158C: Endosomal ferric enterobactin transporter, expressed under conditions of iron deprivation; member of the major facilitator superfamily; expression is regulated by Rcs1p and affected by chloroquine treatment[1][2][3][4]


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  1. Emerson LR, et al. (2002) Relationship between chloroquine toxicity and iron acquisition in Saccharomyces cerevisiae. Antimicrob Agents Chemother 46(3):787-96 SGD PMID 11850263
  2. Heymann P, et al. (2000) A gene of the major facilitator superfamily encodes a transporter for enterobactin (Enb1p) in Saccharomyces cerevisiae. Biometals 13(1):65-72 SGD PMID 10831226
  3. Philpott CC, et al. (2002) The response to iron deprivation in Saccharomyces cerevisiae: expression of siderophore-based systems of iron uptake. Biochem Soc Trans 30(4):698-702 SGD PMID 12196168
  4. Yun CW, et al. (2000) Siderophore-iron uptake in saccharomyces cerevisiae. Identification of ferrichrome and fusarinine transporters. J Biol Chem 275(21):16354-9 SGD PMID 10748025

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