Difference between revisions of "YOL133W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YOL133W YOL133W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005493 YOL133W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''HRT1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''HRT1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|nowrap| Chr XV:70325..70690
 
|nowrap| Chr XV:70325..70690
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000005493
 
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'''Description of {{PAGENAME}}:''' RING finger containing subunit of Skp1-Cullin-F-box ubiquitin protein ligases (SCF); required for Gic2p, Far1p, Sic1p and Cln2p degradation; may tether Cdc34p (a ubiquitin conjugating enzyme or E2) and Cdc53p (a cullin) subunits of SCF<ref name='S000058476'>Zachariae W and Nasmyth K (1999) Whose end is destruction: cell division and the anaphase-promoting complex. Genes Dev 13(16):2039-58 {{SGDpaper|S000058476}} PMID 10465783</ref><ref name='S000056381'>Seol JH, et al. (1999) Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34. Genes Dev 13(12):1614-26 {{SGDpaper|S000056381}} PMID 10385629</ref><ref name='S000044681'>Ohta T, et al. (1999) ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity. Mol Cell 3(4):535-41 {{SGDpaper|S000044681}} PMID 10230407</ref><ref name='S000044434'>Skowyra D, et al. (1999) Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1. Science 284(5414):662-5 {{SGDpaper|S000044434}} PMID 10213692</ref><ref name='S000044433'>Kamura T, et al. (1999) Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase. Science 284(5414):657-61 {{SGDpaper|S000044433}} PMID 10213691</ref><ref name='S000042446'>Blondel M, et al. (2000) Isolation and characterization of HRT1 using a genetic screen for mutants unable to degrade Gic2p in saccharomyces cerevisiae. Genetics 155(3):1033-44
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'''Description of YOL133W:''' RING finger containing subunit of Skp1-Cullin-F-box ubiquitin protein ligases (SCF); required for Gic2p, Far1p, Sic1p and Cln2p degradation; may tether Cdc34p (a ubiquitin conjugating enzyme or E2) and Cdc53p (a cullin) subunits of SCF<ref name='S000042446'>Blondel M, et al. (2000) Isolation and characterization of HRT1 using a genetic screen for mutants unable to degrade Gic2p in saccharomyces cerevisiae. Genetics 155(3):1033-44 {{SGDpaper|S000042446}} PMID 10880467</ref><ref name='S000044433'>Kamura T, et al. (1999) Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase. Science 284(5414):657-61 {{SGDpaper|S000044433}} PMID 10213691</ref><ref name='S000044681'>Ohta T, et al. (1999) ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity. Mol Cell 3(4):535-41 {{SGDpaper|S000044681}} PMID 10230407</ref><ref name='S000056381'>Seol JH, et al. (1999) Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34. Genes Dev 13(12):1614-26 {{SGDpaper|S000056381}} PMID 10385629</ref><ref name='S000044434'>Skowyra D, et al. (1999) Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1. Science 284(5414):662-5 {{SGDpaper|S000044434}} PMID 10213692</ref><ref name='S000058476'>Zachariae W and Nasmyth K (1999) Whose end is destruction: cell division and the anaphase-promoting complex. Genes Dev 13(16):2039-58
  {{SGDpaper|S000042446}} PMID 10880467</ref>
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  {{SGDpaper|S000058476}} PMID 10465783</ref>
 
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J Biol Chem 278(5):3265-74</ref>
 
J Biol Chem 278(5):3265-74</ref>
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YOL133W
Gene name HRT1
Aliases HRT2, RBX1, ROC1
Feature type ORF, Verified
Coordinates Chr XV:70325..70690
Primary SGDID S000005493


Description of YOL133W: RING finger containing subunit of Skp1-Cullin-F-box ubiquitin protein ligases (SCF); required for Gic2p, Far1p, Sic1p and Cln2p degradation; may tether Cdc34p (a ubiquitin conjugating enzyme or E2) and Cdc53p (a cullin) subunits of SCF[1][2][3][4][5][6]




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References

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  1. Blondel M, et al. (2000) Isolation and characterization of HRT1 using a genetic screen for mutants unable to degrade Gic2p in saccharomyces cerevisiae. Genetics 155(3):1033-44 SGD PMID 10880467
  2. Kamura T, et al. (1999) Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase. Science 284(5414):657-61 SGD PMID 10213691
  3. Ohta T, et al. (1999) ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity. Mol Cell 3(4):535-41 SGD PMID 10230407
  4. Seol JH, et al. (1999) Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34. Genes Dev 13(12):1614-26 SGD PMID 10385629
  5. Skowyra D, et al. (1999) Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1. Science 284(5414):662-5 SGD PMID 10213692
  6. Zachariae W and Nasmyth K (1999) Whose end is destruction: cell division and the anaphase-promoting complex. Genes Dev 13(16):2039-58 SGD PMID 10465783

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