Difference between revisions of "YOL111C"

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'''Description of YOL111C:''' Protein required for efficient mating; involved in shmoo formation and nuclear migration in the pre-zygote; associates with ribosomes and interacts with Get4p; has a possible role in insertion of tail-anchored proteins into the ER membrane<ref name='S000115662'>Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 {{SGDpaper|S000115662}} PMID 16702403</ref><ref name='S000113970'>Hu Z, et al. (2006) Mdy2, a ubiquitin-like (UBL)-domain protein, is required for efficient mating in Saccharomyces cerevisiae. J Cell Sci 119(Pt 2):326-38 {{SGDpaper|S000113970}} PMID 16390866</ref><ref name='S000129738'>Jonikas MC, et al. (2009) Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science 323(5922):1693-7
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'''Description of YOL111C:''' Protein with a role in insertion of tail-anchored proteins into the ER membrane; forms a complex with Get4p; required for efficient mating; involved in shmoo formation and nuclear migration in the pre-zygote; associates with ribosomes<ref name='S000132933'>Chang YW, et al. (2010) Crystal structure of Get4-Get5 complex and its interactions with Sgt2, Get3, and Ydj1. J Biol Chem 285(13):9962-70 {{SGDpaper|S000132933}} PMID 20106980</ref><ref name='S000115662'>Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 {{SGDpaper|S000115662}} PMID 16702403</ref><ref name='S000113970'>Hu Z, et al. (2006) Mdy2, a ubiquitin-like (UBL)-domain protein, is required for efficient mating in Saccharomyces cerevisiae. J Cell Sci 119(Pt 2):326-38 {{SGDpaper|S000113970}} PMID 16390866</ref><ref name='S000129738'>Jonikas MC, et al. (2009) Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science 323(5922):1693-7
 
  {{SGDpaper|S000129738}} PMID 19325107</ref>
 
  {{SGDpaper|S000129738}} PMID 19325107</ref>
 
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Revision as of 14:05, 31 August 2010

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Systematic name YOL111C
Gene name MDY2
Aliases GET5, TMA24
Feature type ORF, Verified
Coordinates Chr XV:108896..108258
Primary SGDID S000005471


Description of YOL111C: Protein with a role in insertion of tail-anchored proteins into the ER membrane; forms a complex with Get4p; required for efficient mating; involved in shmoo formation and nuclear migration in the pre-zygote; associates with ribosomes[1][2][3][4]




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References

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  1. Chang YW, et al. (2010) Crystal structure of Get4-Get5 complex and its interactions with Sgt2, Get3, and Ydj1. J Biol Chem 285(13):9962-70 SGD PMID 20106980
  2. Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 SGD PMID 16702403
  3. Hu Z, et al. (2006) Mdy2, a ubiquitin-like (UBL)-domain protein, is required for efficient mating in Saccharomyces cerevisiae. J Cell Sci 119(Pt 2):326-38 SGD PMID 16390866
  4. Jonikas MC, et al. (2009) Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science 323(5922):1693-7 SGD PMID 19325107

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