Difference between revisions of "YOL081W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005441 YOL081W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005441 YOL081W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''IRA2 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''IRA2 ''
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'''Description of YOL081W:''' GTPase-activating protein that negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions, has similarity to Ira1p and human neurofibromin<ref name='S000047724'>Tanaka K, et al. (1990) IRA2, a second gene of Saccharomyces cerevisiae that encodes a protein with a domain homologous to mammalian ras GTPase-activating protein. Mol Cell Biol 10(8):4303-13 {{SGDpaper|S000047724}} PMID 2164637</ref><ref name='S000052853'>Gil R and Seeling JM (1999) Characterization of Saccharomyces cerevisiae strains expressing ira1 mutant alleles modeled after disease-causing mutations in NF1. Mol Cell Biochem 202(1-2):109-18
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'''Description of YOL081W:''' GTPase-activating protein that negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions, has similarity to Ira1p and human neurofibromin<ref name='S000052853'>Gil R and Seeling JM (1999) Characterization of Saccharomyces cerevisiae strains expressing ira1 mutant alleles modeled after disease-causing mutations in NF1. Mol Cell Biochem 202(1-2):109-18 {{SGDpaper|S000052853}} PMID 10706001</ref><ref name='S000047724'>Tanaka K, et al. (1990) IRA2, a second gene of Saccharomyces cerevisiae that encodes a protein with a domain homologous to mammalian ras GTPase-activating protein. Mol Cell Biol 10(8):4303-13
{{SGDpaper|S000052853}} PMID 10706001</ref>
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{{SGDpaper|S000047724}} PMID 2164637</ref>
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YOL081W
Gene name IRA2
Aliases CCS1, GLC4
Feature type ORF, Verified
Coordinates Chr XV:171070..180309
Primary SGDID S000005441


Description of YOL081W: GTPase-activating protein that negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions, has similarity to Ira1p and human neurofibromin[1][2]




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References

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  1. Gil R and Seeling JM (1999) Characterization of Saccharomyces cerevisiae strains expressing ira1 mutant alleles modeled after disease-causing mutations in NF1. Mol Cell Biochem 202(1-2):109-18 SGD PMID 10706001
  2. Tanaka K, et al. (1990) IRA2, a second gene of Saccharomyces cerevisiae that encodes a protein with a domain homologous to mammalian ras GTPase-activating protein. Mol Cell Biol 10(8):4303-13 SGD PMID 2164637

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