YOL051W

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Systematic name YOL051W
Gene name GAL11
Aliases ABE1, MED15, RAR3, SDS4, SPT13
Feature type ORF, Verified
Coordinates Chr XV:234939..238184
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Description of YOL051W: Component of the Mediator complex; interacts with RNA polymerase II and the general transcription factors to form the RNA polymerase II holoenzyme; affects transcription by acting as target of activators and repressors[1][2][3]



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References

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  1. Myers LC and Kornberg RD (2000) Mediator of transcriptional regulation. Annu Rev Biochem 69():729-49 SGD PMID 10966474
  2. Mizuno T and Harashima S (2003) Gal11 is a general activator of basal transcription, whose activity is regulated by the general repressor Sin4 in yeast. Mol Genet Genomics 269(1):68-77 SGD PMID 12715155
  3. Han SJ, et al. (2001) Med9/Cse2 and Gal11 modules are required for transcriptional repression of distinct group of genes. J Biol Chem 276(40):37020-6 SGD PMID 11470794

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