Difference between revisions of "YOL038W"
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| − | '''Description of YOL038W:''' Alpha 4 subunit of the 20S proteasome; may replace alpha 3 subunit (Pre9p) under stress conditions to create a more active proteasomal isoform; GFP-fusion protein relocates from cytosol to the mitochondrial surface upon oxidative stress<ref name=' | + | '''Description of YOL038W:''' Alpha 4 subunit of the 20S proteasome; may replace alpha 3 subunit (Pre9p) under stress conditions to create a more active proteasomal isoform; GFP-fusion protein relocates from cytosol to the mitochondrial surface upon oxidative stress<ref name='S000052602'>Heinemeyer W, et al. (1994) PRE5 and PRE6, the last missing genes encoding 20S proteasome subunits from yeast? Indication for a set of 14 different subunits in the eukaryotic proteasome core. Biochemistry 33(40):12229-37 {{SGDpaper|S000052602}} PMID 7918444</ref><ref name='S000116817'>Rinnerthaler M, et al. (2006) MMI1 (YKL056c, TMA19), the yeast orthologue of the translationally controlled tumor protein (TCTP) has apoptotic functions and interacts with both microtubules and mitochondria. Biochim Biophys Acta 1757(5-6):631-8 {{SGDpaper|S000116817}} PMID 16806052</ref><ref name='S000125713'>Kusmierczyk AR, et al. (2008) A multimeric assembly factor controls the formation of alternative 20S proteasomes. Nat Struct Mol Biol 15(3):237-44 |
| − | {{SGDpaper| | + | {{SGDpaper|S000125713}} PMID 18278055</ref> |
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Revision as of 14:05, 31 March 2009
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| Systematic name | YOL038W |
| Gene name | PRE6 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:255336..256100 |
| Primary SGDID | S000005398 |
Description of YOL038W: Alpha 4 subunit of the 20S proteasome; may replace alpha 3 subunit (Pre9p) under stress conditions to create a more active proteasomal isoform; GFP-fusion protein relocates from cytosol to the mitochondrial surface upon oxidative stress[1][2][3]
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References
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- ↑ Heinemeyer W, et al. (1994) PRE5 and PRE6, the last missing genes encoding 20S proteasome subunits from yeast? Indication for a set of 14 different subunits in the eukaryotic proteasome core. Biochemistry 33(40):12229-37 SGD PMID 7918444
- ↑ Rinnerthaler M, et al. (2006) MMI1 (YKL056c, TMA19), the yeast orthologue of the translationally controlled tumor protein (TCTP) has apoptotic functions and interacts with both microtubules and mitochondria. Biochim Biophys Acta 1757(5-6):631-8 SGD PMID 16806052
- ↑ Kusmierczyk AR, et al. (2008) A multimeric assembly factor controls the formation of alternative 20S proteasomes. Nat Struct Mol Biol 15(3):237-44 SGD PMID 18278055
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