Difference between revisions of "YOL026C"

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'''Description of YOL026C:''' Mitochondrial outer membrane protein, required for assembly of the translocase of the outer membrane (TOM) complex and thereby for mitochondrial protein import; N terminus is exposed to the cytosol: transmembrane segment is highly conserved<ref name='S000077462'>Ishikawa D, et al. (2004) Two novel proteins in the mitochondrial outer membrane mediate beta-barrel protein assembly. J Cell Biol 166(5):621-7 {{SGDpaper|S000077462}} PMID 15326197</ref><ref name='S000076598'>Mnaimneh S, et al. (2004) Exploration of essential gene functions via titratable promoter alleles. Cell 118(1):31-44 {{SGDpaper|S000076598}} PMID 15242642</ref><ref name='S000081337'>Waizenegger T, et al. (2005) Mim1, a protein required for the assembly of the TOM complex of mitochondria. EMBO Rep 6(1):57-62
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'''Description of YOL026C:''' Mitochondrial outer membrane protein, involved in the insertion of TOM (translocase of outer membrane) complex components into the membrane and required for assembly of the TOM complex; mutants display impaired mitochondrial protein import<ref name='S000136084'>Becker T, et al. (2008) Biogenesis of the mitochondrial TOM complex: Mim1 promotes insertion and assembly of signal-anchored receptors. J Biol Chem 283(1):120-7 {{SGDpaper|S000136084}} PMID 17974559</ref><ref name='S000077462'>Ishikawa D, et al. (2004) Two novel proteins in the mitochondrial outer membrane mediate beta-barrel protein assembly. J Cell Biol 166(5):621-7 {{SGDpaper|S000077462}} PMID 15326197</ref><ref name='S000076598'>Mnaimneh S, et al. (2004) Exploration of essential gene functions via titratable promoter alleles. Cell 118(1):31-44 {{SGDpaper|S000076598}} PMID 15242642</ref><ref name='S000081337'>Waizenegger T, et al. (2005) Mim1, a protein required for the assembly of the TOM complex of mitochondria. EMBO Rep 6(1):57-62
 
  {{SGDpaper|S000081337}} PMID 15608614</ref>
 
  {{SGDpaper|S000081337}} PMID 15608614</ref>
 
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Revision as of 14:05, 1 April 2011

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Systematic name YOL026C
Gene name MIM1
Aliases TOM13
Feature type ORF, Verified
Coordinates Chr XV:274353..274012
Primary SGDID S000005386


Description of YOL026C: Mitochondrial outer membrane protein, involved in the insertion of TOM (translocase of outer membrane) complex components into the membrane and required for assembly of the TOM complex; mutants display impaired mitochondrial protein import[1][2][3][4]




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References

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  1. Becker T, et al. (2008) Biogenesis of the mitochondrial TOM complex: Mim1 promotes insertion and assembly of signal-anchored receptors. J Biol Chem 283(1):120-7 SGD PMID 17974559
  2. Ishikawa D, et al. (2004) Two novel proteins in the mitochondrial outer membrane mediate beta-barrel protein assembly. J Cell Biol 166(5):621-7 SGD PMID 15326197
  3. Mnaimneh S, et al. (2004) Exploration of essential gene functions via titratable promoter alleles. Cell 118(1):31-44 SGD PMID 15242642
  4. Waizenegger T, et al. (2005) Mim1, a protein required for the assembly of the TOM complex of mitochondria. EMBO Rep 6(1):57-62 SGD PMID 15608614

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