Difference between revisions of "YOL018C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005378 YOL018C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005378 YOL018C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TLG2 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TLG2 ''

Latest revision as of 07:45, 23 January 2012

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Systematic name YOL018C
Gene name TLG2
Aliases
Feature type ORF, Verified
Coordinates Chr XV:292074..290881
Primary SGDID S000005378


Description of YOL018C: Syntaxin-like t-SNARE that forms a complex with Tlg1p and Vti1p and mediates fusion of endosome-derived vesicles with the late Golgi; binds Vps45p, which prevents Tlg2p degradation and also facilitates t-SNARE complex formation; homologous to mammalian SNARE protein syntaxin 16 (Sx16)[1][2][3][4]




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References

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  1. Bryant NJ and James DE (2001) Vps45p stabilizes the syntaxin homologue Tlg2p and positively regulates SNARE complex formation. EMBO J 20(13):3380-8 SGD PMID 11432826
  2. Coe JG, et al. (1999) A role for Tlg1p in the transport of proteins within the Golgi apparatus of Saccharomyces cerevisiae. Mol Biol Cell 10(7):2407-23 SGD PMID 10397773
  3. Dulubova I, et al. (2002) How Tlg2p/syntaxin 16 'snares' Vps45. EMBO J 21(14):3620-31 SGD PMID 12110575
  4. Struthers MS, et al. (2009) Functional homology of mammalian syntaxin 16 and yeast Tlg2p reveals a conserved regulatory mechanism. J Cell Sci 122(Pt 13):2292-9 SGD PMID 19509055

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