Difference between revisions of "YOL001W"

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'''Description of YOL001W:''' Cyclin, negatively regulates phosphate metabolism; Pho80p-Pho85p (cyclin-CDK complex) phosphorylates Pho4p and Swi5p; deletion of PHO80 leads to aminoglycoside supersensitivity; truncated form of PHO80 affects vacuole inheritance<ref name='S000041722'>Lenburg ME and O'Shea EK (1996) Signaling phosphate starvation. Trends Biochem Sci 21(10):383-7 {{SGDpaper|S000041722}} PMID 8918192</ref><ref name='S000051435'>Wickert S, et al. (1998) A small protein (Ags1p) and the Pho80p-Pho85p kinase complex contribute to aminoglycoside antibiotic resistance of the yeast Saccharomyces cerevisiae. J Bacteriol 180(7):1887-94 {{SGDpaper|S000051435}} PMID 9537389</ref><ref name='S000054927'>Nicolson TA, et al. (1995) A truncated form of the Pho80 cyclin redirects the Pho85 kinase to disrupt vacuole inheritance in S. cerevisiae. J Cell Biol 130(4):835-45 {{SGDpaper|S000054927}} PMID 7642701</ref><ref name='S000061121'>Measday V, et al. (2000) Interactions between Pho85 cyclin-dependent kinase complexes and the Swi5 transcription factor in budding yeast. Mol Microbiol 35(4):825-34
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'''Description of YOL001W:''' Cyclin, interacts with cyclin-dependent kinase Pho85p; regulates the response to nutrient levels and environmental conditions, including the response to phosphate limitation and stress-dependent calcium signaling<ref name='S000048127'>O'Neill EM, et al. (1996) Regulation of PHO4 nuclear localization by the PHO80-PHO85 cyclin-CDK complex. Science 271(5246):209-12 {{SGDpaper|S000048127}} PMID 8539622</ref><ref name='S000114334'>Sopko R, et al. (2006) Mapping pathways and phenotypes by systematic gene overexpression. Mol Cell 21(3):319-30 {{SGDpaper|S000114334}} PMID 16455487</ref><ref name='S000124059'>Huang D, et al. (2007) Pho85, a multifunctional cyclin-dependent protein kinase in budding yeast. Mol Microbiol 66(2):303-14
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  {{SGDpaper|S000061121}} PMID 10692159</ref>
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  {{SGDpaper|S000124059}} PMID 17850263</ref>
 
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Revision as of 14:05, 24 June 2009

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Systematic name YOL001W
Gene name PHO80
Aliases AGS3, TUP7, VAC5, phoR
Feature type ORF, Verified
Coordinates Chr XV:325250..326131
Primary SGDID S000005361


Description of YOL001W: Cyclin, interacts with cyclin-dependent kinase Pho85p; regulates the response to nutrient levels and environmental conditions, including the response to phosphate limitation and stress-dependent calcium signaling[1][2][3]




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References

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  1. ↑ O'Neill EM, et al. (1996) Regulation of PHO4 nuclear localization by the PHO80-PHO85 cyclin-CDK complex. Science 271(5246):209-12 SGD PMID 8539622
  2. ↑ Sopko R, et al. (2006) Mapping pathways and phenotypes by systematic gene overexpression. Mol Cell 21(3):319-30 SGD PMID 16455487
  3. ↑ Huang D, et al. (2007) Pho85, a multifunctional cyclin-dependent protein kinase in budding yeast. Mol Microbiol 66(2):303-14 SGD PMID 17850263

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