YNR047W
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| Systematic name | YNR047W |
| Gene name | FPK1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:708525..711206 |
| Primary SGDID | S000005330 |
Description of YNR047W: Protein kinase proposed to regulate the putative phospholipid translocases Lem3p-Dnf1p/Dnf2p; overexpression interferes with pheromone-induced growth arrest; localizes to the cytoplasm, early endosome/TGN compartments, and plasma membrane[1][2][3]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [2] [4]
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References
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- ↑ Nakano K, et al. (2008) Protein kinases Fpk1p and Fpk2p are novel regulators of phospholipid asymmetry. Mol Biol Cell 19(4):1783-97 SGD PMID 18199685
- ↑ 2.0 2.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ Burchett SA, et al. (2001) Identification of novel pheromone-response regulators through systematic overexpression of 120 protein kinases in yeast. J Biol Chem 276(28):26472-8 SGD PMID 11337509
- ↑ submitted by Jeff Ubersax on 2004-01-29
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