YNR018W

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Systematic name YNR018W
Gene name RCF2
Aliases AIM38
Feature type ORF, Verified
Coordinates Chr XIV:664270..664944
Primary SGDID S000005301


Description of YNR018W: Protein with a role in assembly of respiratory supercomplexes; similar to Rcf1p, and either Rcf1p or Rcf2p is required for late-stage assembly of the Cox12p and Cox13p subunits and for cytochrome c oxidase activity; associates with the cytochrome c oxidase - cytochrome bc1 supercomplex; member of the conserved hypoxia induced gene family; C. elegans ortholog is functional in yeast[1][2]




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References

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  1. Helbig AO, et al. (2009) A three-way proteomics strategy allows differential analysis of yeast mitochondrial membrane protein complexes under anaerobic and aerobic conditions. Proteomics 9(20):4787-98 SGD PMID 19750512
  2. Strogolova V, et al. (2012) Rcf1 and Rcf2, members of the hypoxia induced gene 1 protein family, are critical components of the mitochondrial cytochrome bc1-cytochrome c oxidase supercomplex. Mol Cell Biol () SGD PMID 22310663

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