Difference between revisions of "YNL307C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005251 YNL307C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MCK1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MCK1 '' | ||
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| − | '''Description of YNL307C:''' Protein serine/threonine/tyrosine (dual-specificity) kinase involved in control of chromosome segregation and in regulating entry into meiosis; related to mammalian glycogen synthase kinases of the GSK-3 family<ref name=' | + | '''Description of YNL307C:''' Protein serine/threonine/tyrosine (dual-specificity) kinase involved in control of chromosome segregation and in regulating entry into meiosis; interacts with Clb2p and Mih1p; inhibits Clb2p-Cdk1 activity; related to mammalian glycogen synthase kinases of the GSK-3 family<ref name='S000048421'>Lim MY, et al. (1993) Yeast MCK1 protein kinase autophosphorylates at tyrosine and serine but phosphorylates exogenous substrates at serine and threonine. J Biol Chem 268(28):21155-64 {{SGDpaper|S000048421}} PMID 8407952</ref><ref name='S000150723'>McQueen J, et al. (2012) The Mck1 GSK-3 kinase inhibits the activity of Clb2-Cdk1 post-nuclear division. Cell Cycle 11(18) {{SGDpaper|S000150723}} PMID 22918234</ref><ref name='S000050204'>Neigeborn L and Mitchell AP (1991) The yeast MCK1 gene encodes a protein kinase homolog that activates early meiotic gene expression. Genes Dev 5(4):533-48 {{SGDpaper|S000050204}} PMID 2010083</ref><ref name='S000050205'>Shero JH and Hieter P (1991) A suppressor of a centromere DNA mutation encodes a putative protein kinase (MCK1). Genes Dev 5(4):549-60 |
| − | {{SGDpaper| | + | {{SGDpaper|S000050205}} PMID 2010084</ref> |
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Latest revision as of 14:05, 13 September 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YNL307C |
| Gene name | MCK1 |
| Aliases | CMS1, YPK1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:57573..56446 |
| Primary SGDID | S000005251 |
Description of YNL307C: Protein serine/threonine/tyrosine (dual-specificity) kinase involved in control of chromosome segregation and in regulating entry into meiosis; interacts with Clb2p and Mih1p; inhibits Clb2p-Cdk1 activity; related to mammalian glycogen synthase kinases of the GSK-3 family[1][2][3][4]
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References
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- ↑ Lim MY, et al. (1993) Yeast MCK1 protein kinase autophosphorylates at tyrosine and serine but phosphorylates exogenous substrates at serine and threonine. J Biol Chem 268(28):21155-64 SGD PMID 8407952
- ↑ McQueen J, et al. (2012) The Mck1 GSK-3 kinase inhibits the activity of Clb2-Cdk1 post-nuclear division. Cell Cycle 11(18) SGD PMID 22918234
- ↑ Neigeborn L and Mitchell AP (1991) The yeast MCK1 gene encodes a protein kinase homolog that activates early meiotic gene expression. Genes Dev 5(4):533-48 SGD PMID 2010083
- ↑ Shero JH and Hieter P (1991) A suppressor of a centromere DNA mutation encodes a putative protein kinase (MCK1). Genes Dev 5(4):549-60 SGD PMID 2010084
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