YNL243W

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Systematic name YNL243W
Gene name SLA2
Aliases END4, MOP2
Feature type ORF, Verified
Coordinates Chr XIV:188052..190958


Description of YNL243W: Transmembrane actin-binding protein involved in membrane cytoskeleton assembly and cell polarization; adaptor protein that links actin to clathrin and endocytosis; present in the actin cortical patch of the emerging bud tip; dimer in vivo[1][2][3][4][5]




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References

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  1. Baggett JJ, et al. (2003) The Sla2p talin domain plays a role in endocytosis in Saccharomyces cerevisiae. Genetics 165(4):1661-74 SGD PMID 14704157
  2. Palecek J, et al. (2001) Rpg1p/Tif32p, a subunit of translation initiation factor 3, interacts with actin-associated protein Sla2p. Biochem Biophys Res Commun 282(5):1244-50 SGD PMID 11302750
  3. Munn AL (2001) Molecular requirements for the internalisation step of endocytosis: insights from yeast. Biochim Biophys Acta 1535(3):236-57 SGD PMID 11278164
  4. Yang S, et al. (1999) Sla2p is associated with the yeast cortical actin cytoskeleton via redundant localization signals. Mol Biol Cell 10(7):2265-83 SGD PMID 10397764
  5. Pruyne D and Bretscher A (2000) Polarization of cell growth in yeast. J Cell Sci 113 ( Pt 4)():571-85 SGD PMID 10652251

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