YNL239W

From SGD-Wiki
Revision as of 14:05, 25 February 2010 by SGDwikiBot (talk | contribs) (Automated import of articles)
Jump to: navigation, search

Share your knowledge...Edit this entry! <protect>

Systematic name YNL239W
Gene name LAP3
Aliases BLH1, GAL6, YCP1
Feature type ORF, Verified
Coordinates Chr XIV:200570..201934
Primary SGDID S000005183


Description of YNL239W: Cysteine aminopeptidase with homocysteine-thiolactonase activity; protects cells against homocysteine toxicity; has bleomycin hydrolase activity in vitro; transcription is regulated by galactose via Gal4p; orthologous to human BLMH[1][2][3][4][5]




</protect>

Community Commentary

About Community Commentary. Please share your knowledge!




<protect>

References

See Help:References on how to add references

  1. Ferrando AA, et al. (1996) Cloning and expression analysis of human bleomycin hydrolase, a cysteine proteinase involved in chemotherapy resistance. Cancer Res 56(8):1746-50 SGD PMID 8620487
  2. Kambouris NG, et al. (1992) Cloning and characterization of a cysteine proteinase from Saccharomyces cerevisiae. J Biol Chem 267(30):21570-6 SGD PMID 1400467
  3. Xu HE and Johnston SA (1994) Yeast bleomycin hydrolase is a DNA-binding cysteine protease. Identification, purification, biochemical characterization. J Biol Chem 269(33):21177-83 SGD PMID 8063738
  4. Zheng W, et al. (1997) The cysteine-peptidase bleomycin hydrolase is a member of the galactose regulon in yeast. J Biol Chem 272(48):30350-5 SGD PMID 9374524
  5. Zimny J, et al. (2006) Protective mechanisms against homocysteine toxicity: the role of bleomycin hydrolase. J Biol Chem 281(32):22485-92 SGD PMID 16769724

See Help:Categories on how to add the wiki page for this gene to a Category </protect>