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Systematic name YNL236W
Gene name SIN4
Aliases BEL2, GAL22, MED16, RYE1, SDI3, SSF5, SSN4, TSF3
Feature type ORF, Verified
Coordinates Chr XIV:206930..209854
Primary SGDID S000005180

Description of YNL236W: Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; contributes to both postive and negative transcriptional regulation; dispensible for basal transcription[1][2]


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  1. Li Y, et al. (1995) Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme. Proc Natl Acad Sci U S A 92(24):10864-8 SGD PMID 7479899
  2. Myers LC and Kornberg RD (2000) Mediator of transcriptional regulation. Annu Rev Biochem 69():729-49 SGD PMID 10966474

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