YNL230C
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| Systematic name | YNL230C |
| Gene name | ELA1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:218662..217523 |
| Primary SGDID | S000005174 |
Description of YNL230C: Elongin A; F-box protein that forms a heterodimer with Elc1p and is required for ubiquitin-dependent degradation of the RNA Polymerase II subunit Rpo21p; subunit of the Elongin-Cullin-Socs (ECS) ligase complex[1][2][3]
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References
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- ↑ Botuyan MV, et al. (1999) Binding of elongin A or a von Hippel-Lindau peptide stabilizes the structure of yeast elongin C. Proc Natl Acad Sci U S A 96(16):9033-8 SGD PMID 10430890
- ↑ Gillette TG, et al. (2006) Distinct functions of the ubiquitin-proteasome pathway influence nucleotide excision repair. EMBO J 25(11):2529-38 SGD PMID 16675952
- ↑ Ribar B, et al. (2007) ELA1 and CUL3 are required along with ELC1 for RNA polymerase II polyubiquitylation and degradation in DNA-damaged yeast cells. Mol Cell Biol 27(8):3211-6 SGD PMID 17296727
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