Difference between revisions of "YNL230C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005174 YNL230C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ELA1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ELA1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XIV: | + | |nowrap| Chr XIV:218662..217523 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005174 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005174 | ||
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| − | '''Description of YNL230C:''' Elongin A | + | '''Description of YNL230C:''' Elongin A; F-box protein that forms a heterodimer with Elc1p and is required for ubiquitin-dependent degradation of the RNA Polymerase II subunit Rpo21p; subunit of the Elongin-Cullin-Socs (ECS) ligase complex<ref name='S000040848'>Botuyan MV, et al. (1999) Binding of elongin A or a von Hippel-Lindau peptide stabilizes the structure of yeast elongin C. Proc Natl Acad Sci U S A 96(16):9033-8 {{SGDpaper|S000040848}} PMID 10430890</ref><ref name='S000122537'>Gillette TG, et al. (2006) Distinct functions of the ubiquitin-proteasome pathway influence nucleotide excision repair. EMBO J 25(11):2529-38 {{SGDpaper|S000122537}} PMID 16675952</ref><ref name='S000120848'>Ribar B, et al. (2007) ELA1 and CUL3 are required along with ELC1 for RNA polymerase II polyubiquitylation and degradation in DNA-damaged yeast cells. Mol Cell Biol 27(8):3211-6 |
| − | {{SGDpaper| | + | {{SGDpaper|S000120848}} PMID 17296727</ref> |
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Latest revision as of 07:45, 23 January 2012
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| Systematic name | YNL230C |
| Gene name | ELA1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:218662..217523 |
| Primary SGDID | S000005174 |
Description of YNL230C: Elongin A; F-box protein that forms a heterodimer with Elc1p and is required for ubiquitin-dependent degradation of the RNA Polymerase II subunit Rpo21p; subunit of the Elongin-Cullin-Socs (ECS) ligase complex[1][2][3]
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References
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- ↑ Botuyan MV, et al. (1999) Binding of elongin A or a von Hippel-Lindau peptide stabilizes the structure of yeast elongin C. Proc Natl Acad Sci U S A 96(16):9033-8 SGD PMID 10430890
- ↑ Gillette TG, et al. (2006) Distinct functions of the ubiquitin-proteasome pathway influence nucleotide excision repair. EMBO J 25(11):2529-38 SGD PMID 16675952
- ↑ Ribar B, et al. (2007) ELA1 and CUL3 are required along with ELC1 for RNA polymerase II polyubiquitylation and degradation in DNA-damaged yeast cells. Mol Cell Biol 27(8):3211-6 SGD PMID 17296727
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