Difference between revisions of "YNL223W"
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| − | '''Description of YNL223W:''' | + | '''Description of YNL223W:''' Conserved cysteine protease required for autophagy; cleaves Atg8p to a form required for autophagosome and Cvt vesicle generation<ref name='S000120213'>Meijer WH, et al. (2007) ATG genes involved in non-selective autophagy are conserved from yeast to man, but the selective Cvt and pexophagy pathways also require organism-specific genes. Autophagy 3(2):106-16 {{SGDpaper|S000120213}} PMID 17204848</ref><ref name='S000059897'>Kirisako T, et al. (2000) The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway. J Cell Biol 151(2):263-76 {{SGDpaper|S000059897}} PMID 11038174</ref><ref name='S000051835'>Tsukada M and Ohsumi Y (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 333(1-2):169-74 |
| − | + | {{SGDpaper|S000051835}} PMID 8224160</ref> | |
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Revision as of 07:21, 26 February 2009
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| Systematic name | YNL223W |
| Gene name | ATG4 |
| Aliases | APG4, AUT2 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:227371..228855 |
| Primary SGDID | S000005167 |
Description of YNL223W: Conserved cysteine protease required for autophagy; cleaves Atg8p to a form required for autophagosome and Cvt vesicle generation[1][2][3]
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Contents
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References
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- ↑ Meijer WH, et al. (2007) ATG genes involved in non-selective autophagy are conserved from yeast to man, but the selective Cvt and pexophagy pathways also require organism-specific genes. Autophagy 3(2):106-16 SGD PMID 17204848
- ↑ Kirisako T, et al. (2000) The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway. J Cell Biol 151(2):263-76 SGD PMID 11038174
- ↑ Tsukada M and Ohsumi Y (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 333(1-2):169-74 SGD PMID 8224160
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