Difference between revisions of "YNL102W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005046 YNL102W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005046 YNL102W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''POL1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''POL1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XIV:430089..434495
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|nowrap| Chr XIV:430087..434493
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000005046
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000005046
 
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'''Description of YNL102W:''' Catalytic subunit of the DNA polymerase I alpha-primase complex, required for the initiation of DNA replication during mitotic DNA synthesis and premeiotic DNA synthesis<ref name='S000041750'>Foiani M, et al. (1996) A meiosis-specific protein kinase, Ime2, is required for the correct timing of DNA replication and for spore formation in yeast meiosis. Mol Gen Genet 253(3):278-88 {{SGDpaper|S000041750}} PMID 9003314</ref><ref name='S000058372'>Burgers PM (1998) Eukaryotic DNA polymerases in DNA replication and DNA repair. Chromosoma 107(4):218-27 {{SGDpaper|S000058372}} PMID 9745046</ref><ref name='S000074069'>Gutierrez PJ and Wang TS (2003) Genomic instability induced by mutations in Saccharomyces cerevisiae POL1. Genetics 165(1):65-81
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'''Description of YNL102W:''' Catalytic subunit of the DNA polymerase I alpha-primase complex, required for the initiation of DNA replication during mitotic DNA synthesis and premeiotic DNA synthesis<ref name='S000058372'>Burgers PM (1998) Eukaryotic DNA polymerases in DNA replication and DNA repair. Chromosoma 107(4):218-27 {{SGDpaper|S000058372}} PMID 9745046</ref><ref name='S000041750'>Foiani M, et al. (1996) A meiosis-specific protein kinase, Ime2, is required for the correct timing of DNA replication and for spore formation in yeast meiosis. Mol Gen Genet 253(3):278-88 {{SGDpaper|S000041750}} PMID 9003314</ref><ref name='S000074069'>Gutierrez PJ and Wang TS (2003) Genomic instability induced by mutations in Saccharomyces cerevisiae POL1. Genetics 165(1):65-81
 
  {{SGDpaper|S000074069}} PMID 14504218</ref>
 
  {{SGDpaper|S000074069}} PMID 14504218</ref>
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YNL102W
Gene name POL1
Aliases CDC17, CRT5, HPR3
Feature type ORF, Verified
Coordinates Chr XIV:430087..434493
Primary SGDID S000005046


Description of YNL102W: Catalytic subunit of the DNA polymerase I alpha-primase complex, required for the initiation of DNA replication during mitotic DNA synthesis and premeiotic DNA synthesis[1][2][3]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [4] [5]





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References

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  1. Burgers PM (1998) Eukaryotic DNA polymerases in DNA replication and DNA repair. Chromosoma 107(4):218-27 SGD PMID 9745046
  2. Foiani M, et al. (1996) A meiosis-specific protein kinase, Ime2, is required for the correct timing of DNA replication and for spore formation in yeast meiosis. Mol Gen Genet 253(3):278-88 SGD PMID 9003314
  3. Gutierrez PJ and Wang TS (2003) Genomic instability induced by mutations in Saccharomyces cerevisiae POL1. Genetics 165(1):65-81 SGD PMID 14504218
  4. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  5. submitted by Jeff Ubersax on 2004-01-29

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