YNL048W

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Systematic name YNL048W
Gene name ALG11
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:538174..539820
Primary SGDID S000004993


Description of YNL048W: Alpha-1,2-mannosyltransferase, catalyzes sequential addition of the two terminal alpha 1,2-mannose residues to the Man5GlcNAc2-PP-dolichol intermediate during asparagine-linked glycosylation in the ER[1][2]




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References

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  1. O'Reilly MK, et al. (2006) In vitro evidence for the dual function of Alg2 and Alg11: essential mannosyltransferases in N-linked glycoprotein biosynthesis. Biochemistry 45(31):9593-603 SGD PMID 16878994
  2. Cipollo JF, et al. (2001) The yeast ALG11 gene specifies addition of the terminal alpha 1,2-Man to the Man5GlcNAc2-PP-dolichol N-glycosylation intermediate formed on the cytosolic side of the endoplasmic reticulum. J Biol Chem 276(24):21828-40 SGD PMID 11278778

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