Difference between revisions of "YMR302C"

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'''Description of YMR302C:''' Integral inner mitochondrial membrane protein with a role in maintaining mitochondrial nucleoid structure and number; mutants exhibit an increased rate of mitochondrial DNA escape; shows some sequence similarity to exonucleases<ref name='S000047590'>Thorsness PE and Fox TD (1993) Nuclear mutations in Saccharomyces cerevisiae that affect the escape of DNA from mitochondria to the nucleus. Genetics 134(1):21-8 {{SGDpaper|S000047590}} PMID 8514129</ref><ref name='S000049298'>Hanekamp T and Thorsness PE (1999) YNT20, a bypass suppressor of yme1 yme2, encodes a putative 3'-5' exonuclease localized in mitochondria of Saccharomyces cerevisiae. Curr Genet 34(6):438-48 {{SGDpaper|S000049298}} PMID 9933355</ref><ref name='S000055327'>Hanekamp T and Thorsness PE (1996) Inactivation of YME2/RNA12, which encodes an integral inner mitochondrial membrane protein, causes increased escape of DNA from mitochondria to the nucleus in Saccharomyces cerevisiae. Mol Cell Biol 16(6):2764-71 {{SGDpaper|S000055327}} PMID 8649384</ref><ref name='S000117263'>Park S, et al. (2006) Yme2p is a mediator of nucleoid structure and number in mitochondria of the yeast Saccharomyces cerevisiae. Curr Genet 50(3):173-82
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'''Description of YMR302C:''' Integral inner mitochondrial membrane protein with a role in maintaining mitochondrial nucleoid structure and number; mutants exhibit an increased rate of mitochondrial DNA escape; shows some sequence similarity to exonucleases<ref name='S000055327'>Hanekamp T and Thorsness PE (1996) Inactivation of YME2/RNA12, which encodes an integral inner mitochondrial membrane protein, causes increased escape of DNA from mitochondria to the nucleus in Saccharomyces cerevisiae. Mol Cell Biol 16(6):2764-71 {{SGDpaper|S000055327}} PMID 8649384</ref><ref name='S000049298'>Hanekamp T and Thorsness PE (1999) YNT20, a bypass suppressor of yme1 yme2, encodes a putative 3'-5' exonuclease localized in mitochondria of Saccharomyces cerevisiae. Curr Genet 34(6):438-48 {{SGDpaper|S000049298}} PMID 9933355</ref><ref name='S000117263'>Park S, et al. (2006) Yme2p is a mediator of nucleoid structure and number in mitochondria of the yeast Saccharomyces cerevisiae. Curr Genet 50(3):173-82 {{SGDpaper|S000117263}} PMID 16850347</ref><ref name='S000047590'>Thorsness PE and Fox TD (1993) Nuclear mutations in Saccharomyces cerevisiae that affect the escape of DNA from mitochondria to the nucleus. Genetics 134(1):21-8
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  {{SGDpaper|S000047590}} PMID 8514129</ref>
 
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Revision as of 14:05, 25 February 2010

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Systematic name YMR302C
Gene name YME2
Aliases PRP12, RNA12
Feature type ORF, Verified
Coordinates Chr XIII:872624..870072
Primary SGDID S000004917


Description of YMR302C: Integral inner mitochondrial membrane protein with a role in maintaining mitochondrial nucleoid structure and number; mutants exhibit an increased rate of mitochondrial DNA escape; shows some sequence similarity to exonucleases[1][2][3][4]




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References

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  1. Hanekamp T and Thorsness PE (1996) Inactivation of YME2/RNA12, which encodes an integral inner mitochondrial membrane protein, causes increased escape of DNA from mitochondria to the nucleus in Saccharomyces cerevisiae. Mol Cell Biol 16(6):2764-71 SGD PMID 8649384
  2. Hanekamp T and Thorsness PE (1999) YNT20, a bypass suppressor of yme1 yme2, encodes a putative 3'-5' exonuclease localized in mitochondria of Saccharomyces cerevisiae. Curr Genet 34(6):438-48 SGD PMID 9933355
  3. Park S, et al. (2006) Yme2p is a mediator of nucleoid structure and number in mitochondria of the yeast Saccharomyces cerevisiae. Curr Genet 50(3):173-82 SGD PMID 16850347
  4. Thorsness PE and Fox TD (1993) Nuclear mutations in Saccharomyces cerevisiae that affect the escape of DNA from mitochondria to the nucleus. Genetics 134(1):21-8 SGD PMID 8514129

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