YMR174C
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| Systematic name | YMR174C | |
| Gene name | PAI3 | |
| Aliases | ||
| Feature type | ORF, Verified | |
| Coordinates | Chr XIII:610364..610158 | |
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Description of YMR174C: Cytoplasmic proteinase A inhibitor, dependent on Pbs2p and Hog1p protein kinases for osmotic induction; intrinsically unstructured, N-terminal half becomes ordered in the active site of proteinase A upon contact[1][2][3][4]
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References
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- ↑ Badasso MO, et al. (2000) Purification, co-crystallization and preliminary X--ray analysis of the natural aspartic proteinase inhibitor IA3 complexed with saccharopepsin from Saccharomyces cerevisiae. Acta Crystallogr D Biol Crystallogr 56(Pt 7):915-7 SGD PMID 10930843
- ↑ Beck I, et al. (1980) The intracellular proteinases and their inhibitors in yeast. A mutant with altered regulation of proteinase A inhibitor activity. J Biol Chem 255(10):4821-8 SGD PMID 6989820
- ↑ Phylip LH, et al. (2001) The potency and specificity of the interaction between the IA3 inhibitor and its target aspartic proteinase from Saccharomyces cerevisiae. J Biol Chem 276(3):2023-30 SGD PMID 11042188
- ↑ Miralles VJ and Serrano R (1995) A genomic locus in Saccharomyces cerevisiae with four genes up-regulated by osmotic stress. Mol Microbiol 17(4):653-62 SGD PMID 8801420
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