Difference between revisions of "YMR167W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004777 YMR167W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MLH1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MLH1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr XIII:594885..597194 | |nowrap| Chr XIII:594885..597194 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004777 | ||
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<br> | <br> | ||
| − | '''Description of | + | '''Description of YMR167W:''' Protein required for mismatch repair in mitosis and meiosis, postmeiotic segregation, and spore viability; forms a complex with Pms1p and Msh2p to repair mismatched DNA; human homolog is associated with hereditary non-polyposis colon cancer<ref name='S000057711'>Strand M, et al. (1993) Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair. Nature 365(6443):274-6 {{SGDpaper|S000057711}} PMID 8371783</ref><ref name='S000057619'>Bronner CE, et al. (1994) Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer. Nature 368(6468):258-61 {{SGDpaper|S000057619}} PMID 8145827</ref><ref name='S000052692'>Kolodner RD (1995) Mismatch repair: mechanisms and relationship to cancer susceptibility. Trends Biochem Sci 20(10):397-401 {{SGDpaper|S000052692}} PMID 8533151</ref><ref name='S000041758'>Prolla TA, et al. (1994) MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeast. Science 265(5175):1091-3 |
{{SGDpaper|S000041758}} PMID 8066446</ref> | {{SGDpaper|S000041758}} PMID 8066446</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 08:46, 27 February 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YMR167W |
| Gene name | MLH1 |
| Aliases | PMS2 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:594885..597194 |
| Primary SGDID | S000004777 |
Description of YMR167W: Protein required for mismatch repair in mitosis and meiosis, postmeiotic segregation, and spore viability; forms a complex with Pms1p and Msh2p to repair mismatched DNA; human homolog is associated with hereditary non-polyposis colon cancer[1][2][3][4]
</protect>
Contents
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References
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- ↑ Strand M, et al. (1993) Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair. Nature 365(6443):274-6 SGD PMID 8371783
- ↑ Bronner CE, et al. (1994) Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer. Nature 368(6468):258-61 SGD PMID 8145827
- ↑ Kolodner RD (1995) Mismatch repair: mechanisms and relationship to cancer susceptibility. Trends Biochem Sci 20(10):397-401 SGD PMID 8533151
- ↑ Prolla TA, et al. (1994) MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeast. Science 265(5175):1091-3 SGD PMID 8066446
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