YMR159C
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| Systematic name | YMR159C | |
| Gene name | ATG16 | |
| Aliases | APG15, APG16, CVT11, SAP18 | |
| Feature type | ORF, Verified | |
| Coordinates | Chr XIII:574927..574475 | |
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Description of YMR159C: Protein that interacts with the Atg12p-Atg5p conjugate during formation of the pre-autophagosomal structure; essential for autophagy[1][2][3]
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References
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- ↑ Kuma A, et al. (2002) Formation of the approximately 350-kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast. J Biol Chem 277(21):18619-25 SGD PMID 11897782
- ↑ Suzuki K, et al. (2001) The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation. EMBO J 20(21):5971-81 SGD PMID 11689437
- ↑ Mizushima N, et al. (1999) Apg16p is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway. EMBO J 18(14):3888-96 SGD PMID 10406794
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