Difference between revisions of "YMR110C"
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| − | '''Description of YMR110C:''' | + | '''Description of YMR110C:''' Hexadecenal dehydrogenase; involved in the conversion of sphingosine 1-phosphate breakdown product hexadecenal to hexadecenoic acid; located in the mitochondrial outer membrane and also in lipid particles; has similarity to ALDH3A2, a human fatty aldehyde dehydrogenase (FALDH) mutated in Sjogren-Larsson syndrome, a neurocutaneous disorder<ref name='S000149644'>Nakahara K, et al. (2012) The sjogren-larsson syndrome gene encodes a hexadecenal dehydrogenase of the sphingosine 1-phosphate degradation pathway. Mol Cell 46(4):461-71 {{SGDpaper|S000149644}} PMID 22633490</ref><ref name='S000114057'>Zahedi RP, et al. (2006) Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins. Mol Biol Cell 17(3):1436-50 |
{{SGDpaper|S000114057}} PMID 16407407</ref> | {{SGDpaper|S000114057}} PMID 16407407</ref> | ||
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Latest revision as of 14:05, 5 June 2012
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| Systematic name | YMR110C |
| Gene name | HFD1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:491992..490394 |
| Primary SGDID | S000004716 |
Description of YMR110C: Hexadecenal dehydrogenase; involved in the conversion of sphingosine 1-phosphate breakdown product hexadecenal to hexadecenoic acid; located in the mitochondrial outer membrane and also in lipid particles; has similarity to ALDH3A2, a human fatty aldehyde dehydrogenase (FALDH) mutated in Sjogren-Larsson syndrome, a neurocutaneous disorder[1][2]
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References
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- ↑ Nakahara K, et al. (2012) The sjogren-larsson syndrome gene encodes a hexadecenal dehydrogenase of the sphingosine 1-phosphate degradation pathway. Mol Cell 46(4):461-71 SGD PMID 22633490
- ↑ Zahedi RP, et al. (2006) Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins. Mol Biol Cell 17(3):1436-50 SGD PMID 16407407
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