Difference between revisions of "YMR079W"
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| − | '''Description of YMR079W:''' Phosphatidylinositol/phosphatidylcholine transfer protein involved in | + | '''Description of YMR079W:''' Phosphatidylinositol/phosphatidylcholine transfer protein; involved in regulating PtdIns, PtdCho, and ceramide metabolism, products of which regulate intracellular transport and UPR; functionally homologous to mammalian PITPs<ref name='S000127550'>Mousley CJ, et al. (2008) Trans-Golgi network and endosome dynamics connect ceramide homeostasis with regulation of the unfolded protein response and TOR signaling in yeast. Mol Biol Cell 19(11):4785-803 {{SGDpaper|S000127550}} PMID 18753406</ref><ref name='S000073885'>Schnabl M, et al. (2003) Subcellular localization of yeast Sec14 homologues and their involvement in regulation of phospholipid turnover. Eur J Biochem 270(15):3133-45 {{SGDpaper|S000073885}} PMID 12869188</ref><ref name='S000073107'>Yanagisawa LL, et al. (2002) Activity of specific lipid-regulated ADP ribosylation factor-GTPase-activating proteins is required for Sec14p-dependent Golgi secretory function in yeast. Mol Biol Cell 13(7):2193-206 |
{{SGDpaper|S000073107}} PMID 12134061</ref> | {{SGDpaper|S000073107}} PMID 12134061</ref> | ||
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Revision as of 07:21, 26 February 2009
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| Systematic name | YMR079W |
| Gene name | SEC14 |
| Aliases | PIT1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:424988..426058 |
| Primary SGDID | S000004684 |
Description of YMR079W: Phosphatidylinositol/phosphatidylcholine transfer protein; involved in regulating PtdIns, PtdCho, and ceramide metabolism, products of which regulate intracellular transport and UPR; functionally homologous to mammalian PITPs[1][2][3]
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Contents
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References
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- ↑ Mousley CJ, et al. (2008) Trans-Golgi network and endosome dynamics connect ceramide homeostasis with regulation of the unfolded protein response and TOR signaling in yeast. Mol Biol Cell 19(11):4785-803 SGD PMID 18753406
- ↑ Schnabl M, et al. (2003) Subcellular localization of yeast Sec14 homologues and their involvement in regulation of phospholipid turnover. Eur J Biochem 270(15):3133-45 SGD PMID 12869188
- ↑ Yanagisawa LL, et al. (2002) Activity of specific lipid-regulated ADP ribosylation factor-GTPase-activating proteins is required for Sec14p-dependent Golgi secretory function in yeast. Mol Biol Cell 13(7):2193-206 SGD PMID 12134061
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