YMR070W

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Systematic name YMR070W
Gene name MOT3
Aliases ROX7
Feature type ORF, Verified
Coordinates Chr XIII:409153..410625
Primary SGDID S000004674


Description of YMR070W: Nuclear transcription factor with two Cys2-His2 zinc fingers; involved in repression of a subset of hypoxic genes by Rox1p, repression of several DAN/TIR genes during aerobic growth, and repression of ergosterol biosynthetic genes[1][2][3]




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References

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  1. Grishin AV, et al. (1998) Mot3, a Zn finger transcription factor that modulates gene expression and attenuates mating pheromone signaling in Saccharomyces cerevisiae. Genetics 149(2):879-92 SGD PMID 9611199
  2. Hongay C, et al. (2002) Mot3 is a transcriptional repressor of ergosterol biosynthetic genes and is required for normal vacuolar function in Saccharomyces cerevisiae. EMBO J 21(15):4114-24 SGD PMID 12145211
  3. Sertil O, et al. (2003) Synergistic repression of anaerobic genes by Mot3 and Rox1 in Saccharomyces cerevisiae. Nucleic Acids Res 31(20):5831-7 SGD PMID 14530431

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