Difference between revisions of "YML125C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PGA3 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PGA3 ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''nqr1''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''NQR1''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
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'''Description of YML125C:''' Essential protein required for maturation of Gas1p and Pho8p, proposed to be involved in protein trafficking; GFP-fusion protein localizes to the endoplasmic reticulum; null mutants have a cell separation defect<ref name='S000118289'>Yu L, et al. (2006) A survey of essential gene function in the yeast cell division cycle. Mol Biol Cell 17(11):4736-47 {{SGDpaper|S000118289}} PMID 16943325</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
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'''Description of YML125C:''' Putative cytochrome b5 reductase, localized to the plasma membrane; may be involved in regulation of lifespan; required for maturation of Gas1p and Pho8p, proposed to be involved in protein trafficking<ref name='S000129421'>Jimenez-Hidalgo M, et al. (2009) NQR1 controls lifespan by regulating the promotion of respiratory metabolism in yeast. Aging Cell {{SGDpaper|S000129421}} PMID 19239415</ref><ref name='S000118289'>Yu L, et al. (2006) A survey of essential gene function in the yeast cell division cycle. Mol Biol Cell 17(11):4736-47 {{SGDpaper|S000118289}} PMID 16943325</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
 
  {{SGDpaper|S000074185}} PMID 14562095</ref>
 
  {{SGDpaper|S000074185}} PMID 14562095</ref>
 
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Revision as of 14:05, 3 March 2009

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Systematic name YML125C
Gene name PGA3
Aliases NQR1
Feature type ORF, Verified
Coordinates Chr XIII:21700..20762
Primary SGDID S000004594


Description of YML125C: Putative cytochrome b5 reductase, localized to the plasma membrane; may be involved in regulation of lifespan; required for maturation of Gas1p and Pho8p, proposed to be involved in protein trafficking[1][2][3]




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References

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  1. Jimenez-Hidalgo M, et al. (2009) NQR1 controls lifespan by regulating the promotion of respiratory metabolism in yeast. Aging Cell SGD PMID 19239415
  2. Yu L, et al. (2006) A survey of essential gene function in the yeast cell division cycle. Mol Biol Cell 17(11):4736-47 SGD PMID 16943325
  3. Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095

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